Matches in SemOpenAlex for { <https://semopenalex.org/work/W2465754372> ?p ?o ?g. }
Showing items 1 to 77 of
77
with 100 items per page.
- W2465754372 endingPage "3180" @default.
- W2465754372 startingPage "3175" @default.
- W2465754372 abstract "The anti-mitochondrial antifungal hypothesis implies a link between mitochondrial activity, fungal fruiting structures and susceptibility towards mitochondrial inhibitors. Here it is shown that the oomycete, Phytophthora nicotianae fits the hypothesis. Fruiting structures (zoosporangia) of this oomycete showed increased beta (β)-oxidation when probing levels of 3-hydroxy fatty acids (3-OH oxylipins) with specific polyclonal antibodies. In addition, increased mitochondrial activity was also observed in the zoosporangia when the mitochondrial transmembrane potential (Δψm) probe, Rhodamine 123 was added to the culture. This indicates increased mitochondrial activity in the zoosporangia when compared to the hyphae. When the anti-mitochondrial drug acetylsalicylic acid (ASA) was added to cultures of this oomycete, the zoosporangia were, as expected, most susceptible and were drastically inhibited in the presence of 1 mM of this compound. Similar ASA inhibition results were recorded for P. citrophthora. It is concluded that anti-mitochondrial compounds may find application in combating these devastating plant pathogens and that urgent further research is needed in this direction. Key words: Acetylsalicylic acid, antifungal, anti-mitochondrial, asci, Phytophthora, plant pathogen." @default.
- W2465754372 created "2016-07-22" @default.
- W2465754372 creator A5015489111 @default.
- W2465754372 creator A5037715781 @default.
- W2465754372 creator A5040718542 @default.
- W2465754372 creator A5082413548 @default.
- W2465754372 creator A5083772265 @default.
- W2465754372 date "2011-09-30" @default.
- W2465754372 modified "2023-10-18" @default.
- W2465754372 title "The influence of mitochondrial inhibitors on the life cycle of Phytophthora" @default.
- W2465754372 cites W1486785496 @default.
- W2465754372 cites W1970941522 @default.
- W2465754372 cites W1972640815 @default.
- W2465754372 cites W1977382775 @default.
- W2465754372 cites W1999840011 @default.
- W2465754372 cites W2016882108 @default.
- W2465754372 cites W2051914059 @default.
- W2465754372 cites W2070268240 @default.
- W2465754372 cites W2131361137 @default.
- W2465754372 cites W2145344853 @default.
- W2465754372 cites W2160619010 @default.
- W2465754372 doi "https://doi.org/10.5897/ajmr11.139" @default.
- W2465754372 hasPublicationYear "2011" @default.
- W2465754372 type Work @default.
- W2465754372 sameAs 2465754372 @default.
- W2465754372 citedByCount "1" @default.
- W2465754372 countsByYear W24657543722015 @default.
- W2465754372 crossrefType "journal-article" @default.
- W2465754372 hasAuthorship W2465754372A5015489111 @default.
- W2465754372 hasAuthorship W2465754372A5037715781 @default.
- W2465754372 hasAuthorship W2465754372A5040718542 @default.
- W2465754372 hasAuthorship W2465754372A5082413548 @default.
- W2465754372 hasAuthorship W2465754372A5083772265 @default.
- W2465754372 hasBestOaLocation W24657543721 @default.
- W2465754372 hasConcept C2776460866 @default.
- W2465754372 hasConcept C2776620211 @default.
- W2465754372 hasConcept C2777537739 @default.
- W2465754372 hasConcept C2779548794 @default.
- W2465754372 hasConcept C2780100698 @default.
- W2465754372 hasConcept C2780644372 @default.
- W2465754372 hasConcept C28859421 @default.
- W2465754372 hasConcept C55493867 @default.
- W2465754372 hasConcept C59822182 @default.
- W2465754372 hasConcept C86803240 @default.
- W2465754372 hasConcept C89423630 @default.
- W2465754372 hasConceptScore W2465754372C2776460866 @default.
- W2465754372 hasConceptScore W2465754372C2776620211 @default.
- W2465754372 hasConceptScore W2465754372C2777537739 @default.
- W2465754372 hasConceptScore W2465754372C2779548794 @default.
- W2465754372 hasConceptScore W2465754372C2780100698 @default.
- W2465754372 hasConceptScore W2465754372C2780644372 @default.
- W2465754372 hasConceptScore W2465754372C28859421 @default.
- W2465754372 hasConceptScore W2465754372C55493867 @default.
- W2465754372 hasConceptScore W2465754372C59822182 @default.
- W2465754372 hasConceptScore W2465754372C86803240 @default.
- W2465754372 hasConceptScore W2465754372C89423630 @default.
- W2465754372 hasIssue "20" @default.
- W2465754372 hasLocation W24657543721 @default.
- W2465754372 hasOpenAccess W2465754372 @default.
- W2465754372 hasPrimaryLocation W24657543721 @default.
- W2465754372 hasRelatedWork W2088610319 @default.
- W2465754372 hasRelatedWork W2090604822 @default.
- W2465754372 hasRelatedWork W2090780984 @default.
- W2465754372 hasRelatedWork W2120578542 @default.
- W2465754372 hasRelatedWork W2178087988 @default.
- W2465754372 hasRelatedWork W2912450785 @default.
- W2465754372 hasRelatedWork W3039282603 @default.
- W2465754372 hasRelatedWork W3185044403 @default.
- W2465754372 hasRelatedWork W4206657756 @default.
- W2465754372 hasRelatedWork W4226307560 @default.
- W2465754372 hasVolume "5" @default.
- W2465754372 isParatext "false" @default.
- W2465754372 isRetracted "false" @default.
- W2465754372 magId "2465754372" @default.
- W2465754372 workType "article" @default.