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- W2466389601 abstract "To determine if rotavirus interferes with the multiplication of poliovirus, and hence the efficiency of the polio vaccine, the effect of timing and concentration of Simian rotavirus (SSA-11) on polio-1 infection in MA-104 cells was studied in vitro by evaluating the cytopathic effect, the reduction of the infectivity titers and the visualization of viral particles by electron microscopy. We found that poliovirus 1 was able to replicate when the challenge dose was administered within the first 8 h following SA-11 infection and with titers ten times lower than those of rotavirus. Hence, non-interference effect was observed in this in vitro model." @default.
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- W2466389601 date "1992-01-01" @default.
- W2466389601 modified "2023-09-23" @default.
- W2466389601 title "Lack of in vitro interference between SA-11 rotavirus and attenuated poliovirus type 1." @default.
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