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- W2466693783 abstract "Patterns of variation and covariation within populations can influence how characters respond to natural selection and random genetic drift and so constrain the ability of natural selection to modify the phenotype. We examined several potential developmental and functional explana- tions of character covariation throughout ontogeny using known-age samples of the cotton rat (Sigmodonfulviventer) to identify the causes of covariation and to assess the variability of patterns of covariation throughout postnatal growth. Competing developmental and functional models were fit to samples of orofacial and neurocranial measures by confirmatory factor analysis and evaluated for their ability to reconstruct observed variance-covariance matrices. Samples of successive ages were simultaneously fit to a common model to test the hypothesis that the patterns of developmental and functional integration were invariant between ages. Orofacial characters derived from the same branchial-arch primordium covary early in ontogeny. Subsequently, there is a repatterning of integration that may reflect a transition from developmental to functional sources of integration. Neurocranial characters exhibit even more variation in patterns of covariation: initially, characters appear to comprise a single integrated unit; before puberty, they appear to respond to localized bone growth; after puberty, they form separate calvarial and basi- cranial components. This ontogenetic variation in patterns of covariation suggests that develop- mental constraints are transient and flexible and that the consequences of selection may depend upon the age at which it acts." @default.
- W2466693783 created "2016-07-22" @default.
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- W2466693783 date "1989-01-01" @default.
- W2466693783 modified "2023-09-26" @default.
- W2466693783 title "FUNCTIONAL INTEGRATION IN SKULLS OF SIGMODON FUL VI VENTER" @default.
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