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- W2466778856 abstract "A series of lipophilic teicoplanin pseudoaglycon derivatives, including alkyl-, aryl-, calixarene- and protected sugar-containing conjugates, were prepared using azide-alkyne click chemistry. Out of the conditions applied, the CuSO4-ascorbate reagent system proved to be more efficient than the Cu(I)I-Et3N-mediated reaction. Some of the new compounds have high in vitro activity against glycopeptide-resistant Gram-positive bacteria, including vanA-positive Enterococcus faecalis. A few of them also display promising in vitro anti-influenza activity." @default.
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- W2466778856 date "2016-06-29" @default.
- W2466778856 modified "2023-10-18" @default.
- W2466778856 title "Synthesis and biological evaluation of lipophilic teicoplanin pseudoaglycon derivatives containing a substituted triazole function" @default.
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- W2466778856 doi "https://doi.org/10.1038/ja.2016.80" @default.
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