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- W2467006726 abstract "The first step in the evaluation of diffuse parenchymal lung disease (DPLD) should be to establish its activity. The currently accepted parameters are clinical, changes in lung physiology, computerized tomographic (CT) appearance, and lung biopsy. Gallium 67 scintigraphy has been felt to be controversial. We reviewed 17 cases of DPLD and documented gallium 67 scan results with evidence of activity as reflected by 10% change in pulmonary function tests, evidence of alveolitis on CT and cellular proliferation on lung biopsies. Fourteen cases had positive Gallium scans and active DPLD (true positives), one had positive scan and active DPLD (false positive), and one had negative scan and active DPLD (false negative), and one had a negative scintigraphy and no evidence of activity (true negative). The sensitivity of the gallium 67 scan was 93%, the specificity was 50%, the positive predictive value was 93%, negative predictive value was 50%, the likelihood ratio for positive was 1.86, and the negative likelihood was 0.13. Gallium scan results were also correlated with a clinical, radiological, physiological, pathological score (CRPP), yielded a p value of 0.058. We conclude that the gallium67 scintigraphy is a useful method to establish inflammatory activity in DPLD." @default.
- W2467006726 created "2016-07-22" @default.
- W2467006726 date "2004-01-01" @default.
- W2467006726 modified "2023-09-25" @default.
- W2467006726 title "Gallium Scan Predicts Activity Of Diffuse Parenchymal Lung Disease" @default.
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- W2467006726 doi "https://doi.org/10.5580/d4f" @default.
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