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- W2467136291 abstract "Objective To determine whether cerebroplacental ratio, an indicator of fetal cerebral redistribution (FCR), predicts adverse results for neurodevelopment in intrauterine growth restriction (IUGR) infants. Methods In a cohort of 5,702 infants, 64 were IUGR born at term with FCR. Five were excluded. Of the remainder, 32 presented an abnormal cerebroplacental ratio (IUGR-A) and 27 a normal one (IUGR-B). The controls were 61 appropriate-for-gestational-age children. Cognitive and academic outcomes and the odds ratio of lower academic scores were assessed by multivariate analysis of covariance and logistic regression. Results IUGR-A children presented deficits in cognitive functioning and academic achievement in all domains. IUGR-B children presented slight deficits. Suboptimal cognitive functioning in IUGR-A was more marked in working memory. Abnormal cerebroplacental ratio predicted low academic scores in IUGR-A. Conclusions FCR is a risk factor for IUGR infants, and cerebroplacental ratio identifies those most severely affected. Intervention programs may produce benefits in early-middle childhood." @default.
- W2467136291 created "2016-07-22" @default.
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- W2467136291 date "2016-06-24" @default.
- W2467136291 modified "2023-10-18" @default.
- W2467136291 title "Cognitive Functioning and Academic Achievement in Children Aged 6–8 Years, Born at Term After Intrauterine Growth Restriction and Fetal Cerebral Redistribution" @default.
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- W2467136291 doi "https://doi.org/10.1093/jpepsy/jsw060" @default.
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