Matches in SemOpenAlex for { <https://semopenalex.org/work/W2467227568> ?p ?o ?g. }
Showing items 1 to 84 of
84
with 100 items per page.
- W2467227568 endingPage "604" @default.
- W2467227568 startingPage "599" @default.
- W2467227568 abstract "OBJECTIVE To assess the role of anti-CCP antibodies in synovial fluid (SF) of psoriatic arthritis (PsA) patients by analysing their association with different clinical patterns of the disease. METHODS Seventy-five patients with a knee-joint effusion were studied, including 31 PsA patients, 29 rheumatoid arthritis (RA) and 15 osteoarthritis (OA) patients. SF and paired serum samples were stored at -70 degrees C until IgG anti-CCP and total IgG determination. The pattern of PsA articular involvement was defined as mono-, oligo-, polyarticular or axial. RESULTS Lower levels of IgG anti-CCP antibodies in SF (p < 0.01) and serum (p < 0.005) were found in PsA respect to RA patients without difference with OA. We found a higher SF/serum ratio for anti-CCP compared to the SF/serum ratio for total IgG in PsA (p < 0.0005) as well as in RA and OA. The correction of anti-CCP concentration in SF as IgG anti-CCP (unit) / total IgG revealed lower (p < 0.002) values in PsA patients with respect to RA patients. In PsA group, values of anti-CCP antibodies, SF/serum ratio of anti-CCP and anti-CCP/IgG above the cut-off were found in 5, 6 and 2 SF samples respectively. The presence or absence of anti-CCP antibodies did not discriminate a particular clinical subset. CONCLUSIONS In conclusion, strengthening the concept of local production of anti-CCP antibodies within the joint space, our results suggest that anti-CCP antibody detection in SF should take into account corrections such as total amount of corresponding immunoglobulin or SF/serum ratio. In our study, the presence or absence of anti-CCP antibodies did not discriminate a particular clinical subset, but further longitudinal studies are required to clarify the clinical role of anti-CCP in PsA." @default.
- W2467227568 created "2016-07-22" @default.
- W2467227568 creator A5004485732 @default.
- W2467227568 creator A5039970068 @default.
- W2467227568 creator A5051985825 @default.
- W2467227568 creator A5058230766 @default.
- W2467227568 creator A5087114501 @default.
- W2467227568 date "2007-07-01" @default.
- W2467227568 modified "2023-09-24" @default.
- W2467227568 title "Anti-cyclic citrullinated peptide antibody determination in synovial fluid of psoriatic arthritis." @default.
- W2467227568 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17888217" @default.
- W2467227568 hasPublicationYear "2007" @default.
- W2467227568 type Work @default.
- W2467227568 sameAs 2467227568 @default.
- W2467227568 citedByCount "2" @default.
- W2467227568 countsByYear W24672275682022 @default.
- W2467227568 crossrefType "journal-article" @default.
- W2467227568 hasAuthorship W2467227568A5004485732 @default.
- W2467227568 hasAuthorship W2467227568A5039970068 @default.
- W2467227568 hasAuthorship W2467227568A5051985825 @default.
- W2467227568 hasAuthorship W2467227568A5058230766 @default.
- W2467227568 hasAuthorship W2467227568A5087114501 @default.
- W2467227568 hasConcept C126322002 @default.
- W2467227568 hasConcept C141071460 @default.
- W2467227568 hasConcept C142724271 @default.
- W2467227568 hasConcept C159654299 @default.
- W2467227568 hasConcept C163430725 @default.
- W2467227568 hasConcept C203014093 @default.
- W2467227568 hasConcept C204787440 @default.
- W2467227568 hasConcept C2776164576 @default.
- W2467227568 hasConcept C2776232647 @default.
- W2467227568 hasConcept C2776260265 @default.
- W2467227568 hasConcept C2776268809 @default.
- W2467227568 hasConcept C2777077863 @default.
- W2467227568 hasConcept C2777575956 @default.
- W2467227568 hasConcept C71924100 @default.
- W2467227568 hasConcept C90924648 @default.
- W2467227568 hasConceptScore W2467227568C126322002 @default.
- W2467227568 hasConceptScore W2467227568C141071460 @default.
- W2467227568 hasConceptScore W2467227568C142724271 @default.
- W2467227568 hasConceptScore W2467227568C159654299 @default.
- W2467227568 hasConceptScore W2467227568C163430725 @default.
- W2467227568 hasConceptScore W2467227568C203014093 @default.
- W2467227568 hasConceptScore W2467227568C204787440 @default.
- W2467227568 hasConceptScore W2467227568C2776164576 @default.
- W2467227568 hasConceptScore W2467227568C2776232647 @default.
- W2467227568 hasConceptScore W2467227568C2776260265 @default.
- W2467227568 hasConceptScore W2467227568C2776268809 @default.
- W2467227568 hasConceptScore W2467227568C2777077863 @default.
- W2467227568 hasConceptScore W2467227568C2777575956 @default.
- W2467227568 hasConceptScore W2467227568C71924100 @default.
- W2467227568 hasConceptScore W2467227568C90924648 @default.
- W2467227568 hasIssue "4" @default.
- W2467227568 hasLocation W24672275681 @default.
- W2467227568 hasLocation W24672275682 @default.
- W2467227568 hasOpenAccess W2467227568 @default.
- W2467227568 hasPrimaryLocation W24672275681 @default.
- W2467227568 hasRelatedWork W175199685 @default.
- W2467227568 hasRelatedWork W1969337384 @default.
- W2467227568 hasRelatedWork W1977896201 @default.
- W2467227568 hasRelatedWork W1991246900 @default.
- W2467227568 hasRelatedWork W2007654725 @default.
- W2467227568 hasRelatedWork W2025939140 @default.
- W2467227568 hasRelatedWork W202906702 @default.
- W2467227568 hasRelatedWork W2053144157 @default.
- W2467227568 hasRelatedWork W2058481614 @default.
- W2467227568 hasRelatedWork W2068780189 @default.
- W2467227568 hasRelatedWork W2103021172 @default.
- W2467227568 hasRelatedWork W2109456961 @default.
- W2467227568 hasRelatedWork W2139180477 @default.
- W2467227568 hasRelatedWork W2143231593 @default.
- W2467227568 hasRelatedWork W2148417990 @default.
- W2467227568 hasRelatedWork W2176881041 @default.
- W2467227568 hasRelatedWork W2401246870 @default.
- W2467227568 hasRelatedWork W2407734107 @default.
- W2467227568 hasRelatedWork W2417569001 @default.
- W2467227568 hasRelatedWork W28934433 @default.
- W2467227568 hasVolume "25" @default.
- W2467227568 isParatext "false" @default.
- W2467227568 isRetracted "false" @default.
- W2467227568 magId "2467227568" @default.
- W2467227568 workType "article" @default.