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• W2467424103 abstract "Purpose: To report the efficacy of mycophenolate mofetil (MMF) as adjunctive therapy for the treatment of multiple sclerosis (MS)-associated uveitis.Methods: In this retrospective, interventional case series, patients with MS-associated uveitis who were treated by MMF as an adjunct therapy to systemic corticosteroid were studied. Patients’ demographics, clinical course, response to treatment, and complications were assessed.Results: A total of 30 eyes of 15 patients with a mean age of 34.5 ± 8.3 years were studied. In three patients (20%), onset of uveitis preceded the diagnosis of MS. The course of MS was relapsing–remitting in 11 patients (73.3%) and secondary progressive in four patients (26.7%). At 1 year after institution of MMF, all the patients were on oral prednisolone ≤ 7.5 mg/day, all eyes were quiet without macular edema, and 53.3% of eyes gained visual improvement. Supplemental periocular and intraocular injections were needed during the first 6 months after starting MMF therapy. The systemic adverse effects were transient and minor in severity.Conclusions: MMF had beneficial effects on vision and intraocular inflammation with an acceptable safety profile." @default.
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• W2467424103 date "2016-07-05" @default.
• W2467424103 modified "2023-10-14" @default.
• W2467424103 title "Mycophenolate Mofetil for the Treatment of Multiple Sclerosis-associated Uveitis" @default.
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• W2467424103 doi "https://doi.org/10.1080/09273948.2016.1178302" @default.
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