FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2467618511> ?p ?o ?g. }

• W2467618511 endingPage "130" @default.
• W2467618511 startingPage "116" @default.
• W2467618511 abstract "Central sensitivity syndromes (CSS) share features of similar multiple symptoms, virtually unknown mechanisms and lack of effective treatments. The CSS nomenclature was chosen over alternatives because it focused on a putative physiological mechanism of central sensitization common to disorders such as fibromyalgia, irritable bowel syndrome, vulvodynia and temporomandibular disorder. Increasing evidence from multiple biological systems suggests a further development. In this new model central sensitization is part of a ensemble that includes also the symptoms of widespread pain, fatigue, unrefreshing sleep and dyscognition. The main feature is an intrinsic program that produces this ensemble to guide behavior to restore normal function in conditions that threaten survival. The well known “illness response” is a classic example that is triggered in response to the specific threat of viral infection. The major leap for this model in the context of CSS is that the symptom complex is not a reactive result of pathology, but a purposeful feeling state enlisted to combat pathology. Once triggered, this state is produced by potential mechanisms that likely include contributions of the peripheral and central immune systems, as well as stress response systems such as the autonomic system and the hypothalamic–pituitary–adrenal (HPA) axis. These act in concert to alter behavior in a beneficial direction. This concept explains similar symptoms for many triggering conditions, the poorly understood pathology, and the resistance to treatment. Keywords: Autonomic, central sensitivity syndromes, fibromyalgia, functional somatic disorders, hypothalamic–pituitary– adrenal axis, illness response, immune, protective homeostasis, purposeful feeling state, stress." @default.
• W2467618511 created "2016-07-22" @default.
• W2467618511 creator A5035220104 @default.
• W2467618511 creator A5070468727 @default.
• W2467618511 date "2015-07-02" @default.
• W2467618511 modified "2023-10-14" @default.
• W2467618511 title "Programmed Symptoms: Disparate Effects United by Purpose" @default.
• W2467618511 cites W1437957709 @default.
• W2467618511 cites W1489805892 @default.
• W2467618511 cites W1593244742 @default.
• W2467618511 cites W1639792556 @default.
• W2467618511 cites W1807844052 @default.
• W2467618511 cites W183007366 @default.
• W2467618511 cites W1845241525 @default.
• W2467618511 cites W1964719865 @default.
• W2467618511 cites W1966219326 @default.
• W2467618511 cites W1967034335 @default.
• W2467618511 cites W1967296243 @default.
• W2467618511 cites W1967852558 @default.
• W2467618511 cites W1970076899 @default.
• W2467618511 cites W1974207924 @default.
• W2467618511 cites W1975493402 @default.
• W2467618511 cites W1975745651 @default.
• W2467618511 cites W1978053355 @default.
• W2467618511 cites W1979753077 @default.
• W2467618511 cites W1981291046 @default.
• W2467618511 cites W1982105720 @default.
• W2467618511 cites W1987445189 @default.
• W2467618511 cites W1988347806 @default.
• W2467618511 cites W1989837855 @default.
• W2467618511 cites W1990212639 @default.
• W2467618511 cites W1991051558 @default.
• W2467618511 cites W1993250597 @default.
• W2467618511 cites W1993492728 @default.
• W2467618511 cites W1996108985 @default.
• W2467618511 cites W1997198684 @default.
• W2467618511 cites W1997259358 @default.
• W2467618511 cites W1998221046 @default.
• W2467618511 cites W1998713427 @default.
• W2467618511 cites W1998806270 @default.
• W2467618511 cites W2001952147 @default.
• W2467618511 cites W2002876517 @default.
• W2467618511 cites W2007502001 @default.
• W2467618511 cites W2008760801 @default.
• W2467618511 cites W2008997579 @default.
• W2467618511 cites W2009746022 @default.
• W2467618511 cites W2011140328 @default.
• W2467618511 cites W2011875337 @default.
• W2467618511 cites W2012707242 @default.
• W2467618511 cites W2012968633 @default.
• W2467618511 cites W2013924802 @default.
• W2467618511 cites W2015847657 @default.
• W2467618511 cites W2017903078 @default.
• W2467618511 cites W2018613168 @default.
• W2467618511 cites W2018811661 @default.
• W2467618511 cites W2019865493 @default.
• W2467618511 cites W2022404177 @default.
• W2467618511 cites W2023637447 @default.
• W2467618511 cites W2026256841 @default.
• W2467618511 cites W2026429915 @default.
• W2467618511 cites W2026863533 @default.
• W2467618511 cites W2027105915 @default.
• W2467618511 cites W2028451998 @default.
• W2467618511 cites W2028953043 @default.
• W2467618511 cites W2032118892 @default.
• W2467618511 cites W2032867586 @default.
• W2467618511 cites W2034140197 @default.
• W2467618511 cites W2035605437 @default.
• W2467618511 cites W2035945979 @default.
• W2467618511 cites W2036255519 @default.
• W2467618511 cites W2040493240 @default.
• W2467618511 cites W2041438235 @default.
• W2467618511 cites W2041439089 @default.
• W2467618511 cites W2041747655 @default.
• W2467618511 cites W2041796079 @default.
• W2467618511 cites W2041860989 @default.
• W2467618511 cites W2043573126 @default.
• W2467618511 cites W2047570180 @default.
• W2467618511 cites W2048378583 @default.
• W2467618511 cites W2049499319 @default.
• W2467618511 cites W2049894288 @default.
• W2467618511 cites W2050545698 @default.
• W2467618511 cites W2051356055 @default.
• W2467618511 cites W2051975061 @default.
• W2467618511 cites W2053715625 @default.
• W2467618511 cites W2056014583 @default.
• W2467618511 cites W2056552590 @default.
• W2467618511 cites W2057319553 @default.
• W2467618511 cites W2057746847 @default.
• W2467618511 cites W2059140871 @default.
• W2467618511 cites W2060293501 @default.
• W2467618511 cites W2060913403 @default.
• W2467618511 cites W2061404967 @default.
• W2467618511 cites W2062700118 @default.
• W2467618511 cites W2062989629 @default.
• W2467618511 cites W2065514611 @default.
• W2467618511 cites W2067628618 @default.
• W2467618511 cites W2068324896 @default.

• next