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- W2467619758 abstract "The interaction of 20 antibiotics with the cationic surfactant cetyltrimethylammonium bromide (CTAB) was studied by charge-transfer reversed-phase chromatography carried out on impregnated alumina layers using water-methanol mixtures as eluents. The lipophilicity and specific hydrophobic surface area of antibiotics and the relative strength of their interaction with CTAB was calculated. CTAB interacted with 10 antibiotics the antibiotic--CTAB complex generally being more hydrophilic than the uncomplexed molecule. The relative strength of interaction depended considerably on the molecular structure of the antibiotics. Significant linear correlation was found between the lipophilicity of antibiotics and their capacity to interact with CTAB indicating the involvement of hydrophobic forces in the interaction." @default.
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- W2467619758 date "2000-04-01" @default.
- W2467619758 modified "2023-09-27" @default.
- W2467619758 title "Charge-transfer chromatographic study of the interaction of antibiotics with cetyltrimethylammonium bromide." @default.
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