FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2467701455> ?p ?o ?g. }

• W2467701455 abstract "Abstract Stenotrophomonas maltophilia is an opportunistic pathogen that causes respiratory and urinary tract infections, as well as wound infections in immunocompromised patients. This pathogen is difficult to treat due to increased resistance to many antimicrobial agents. We investigated the in vitro biofilm formation of S. maltophilia , including effects of fluoroquinolones (FQs) and azithromycin on biofilm formation. The organism initiated attachment to polystyrene surfaces after a 4 h incubation period and reached maximal growth at 18–24 h. In the presence of FQs (moxifloxacin, levofloxacin or ciprofloxacin), the biofilm biomass was significantly reduced ( P < 0.05). A lower concentration of moxifloxacin (10 μg/mL) exhibited a better inhibiting effect on biofilm formation than 100 μg/mL (P < 0.01), but with no difference in effect compared to the 50 μg/mL concentration (P > 0.05). However, the inhibitory effects of 10 μg/mL of levofloxacin or ciprofloxacin were slightly less pronounced than those of the higher concentrations. A combination of azithromycin and FQs significantly reduced the biofilm inhibiting effect on S. maltophilia preformed biofilms compared to azithromycin or FQs alone. We conclude that early use of clinically acceptable concentrations of FQs, especially moxifloxacin (10 μg/mL), may possibly inhibit biofilm formation by S. maltophilia. Our study provides an experimental basis for a possible optimal treatment strategy for S. maltophilia biofilm-related infections." @default.
• W2467701455 created "2016-07-22" @default.
• W2467701455 creator A5020319484 @default.
• W2467701455 creator A5026683899 @default.
• W2467701455 creator A5080782442 @default.
• W2467701455 creator A5082255460 @default.
• W2467701455 creator A5088254472 @default.
• W2467701455 date "2016-07-13" @default.
• W2467701455 modified "2023-10-03" @default.
• W2467701455 title "Effects of Fluoroquinolones and Azithromycin on Biofilm Formation of Stenotrophomonas maltophilia" @default.
• W2467701455 cites W1567508932 @default.
• W2467701455 cites W1929451968 @default.
• W2467701455 cites W1977668902 @default.
• W2467701455 cites W1986326641 @default.
• W2467701455 cites W2016158447 @default.
• W2467701455 cites W2040526505 @default.
• W2467701455 cites W2041314827 @default.
• W2467701455 cites W2044234461 @default.
• W2467701455 cites W2055758849 @default.
• W2467701455 cites W2059845527 @default.
• W2467701455 cites W2062719893 @default.
• W2467701455 cites W2083047705 @default.
• W2467701455 cites W2083131950 @default.
• W2467701455 cites W2090581372 @default.
• W2467701455 cites W2097445101 @default.
• W2467701455 cites W2098300761 @default.
• W2467701455 cites W2099759208 @default.
• W2467701455 cites W2103561095 @default.
• W2467701455 cites W2108106075 @default.
• W2467701455 cites W2115933619 @default.
• W2467701455 cites W2122806134 @default.
• W2467701455 cites W2128988512 @default.
• W2467701455 cites W2135039738 @default.
• W2467701455 cites W2137797971 @default.
• W2467701455 cites W2140849505 @default.
• W2467701455 cites W2145958601 @default.
• W2467701455 cites W2148967763 @default.
• W2467701455 cites W2152130519 @default.
• W2467701455 cites W2155246554 @default.
• W2467701455 cites W2155317724 @default.
• W2467701455 cites W2157351476 @default.
• W2467701455 cites W2161889015 @default.
• W2467701455 cites W2162950281 @default.
• W2467701455 cites W2166987806 @default.
• W2467701455 cites W2170537056 @default.
• W2467701455 cites W2171624472 @default.
• W2467701455 cites W2285623417 @default.
• W2467701455 doi "https://doi.org/10.1038/srep29701" @default.
• W2467701455 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4942784" @default.
• W2467701455 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/27405358" @default.
• W2467701455 hasPublicationYear "2016" @default.
• W2467701455 type Work @default.
• W2467701455 sameAs 2467701455 @default.
• W2467701455 citedByCount "27" @default.
• W2467701455 countsByYear W24677014552017 @default.
• W2467701455 countsByYear W24677014552018 @default.
• W2467701455 countsByYear W24677014552019 @default.
• W2467701455 countsByYear W24677014552020 @default.
• W2467701455 countsByYear W24677014552021 @default.
• W2467701455 countsByYear W24677014552022 @default.
• W2467701455 countsByYear W24677014552023 @default.
• W2467701455 crossrefType "journal-article" @default.
• W2467701455 hasAuthorship W2467701455A5020319484 @default.
• W2467701455 hasAuthorship W2467701455A5026683899 @default.
• W2467701455 hasAuthorship W2467701455A5080782442 @default.
• W2467701455 hasAuthorship W2467701455A5082255460 @default.
• W2467701455 hasAuthorship W2467701455A5088254472 @default.
• W2467701455 hasBestOaLocation W24677014551 @default.
• W2467701455 hasConcept C185592680 @default.
• W2467701455 hasConcept C2776352461 @default.
• W2467701455 hasConcept C2776460866 @default.
• W2467701455 hasConcept C2777637488 @default.
• W2467701455 hasConcept C2778049240 @default.
• W2467701455 hasConcept C2778512257 @default.
• W2467701455 hasConcept C2778836808 @default.
• W2467701455 hasConcept C2778907293 @default.
• W2467701455 hasConcept C2781276175 @default.
• W2467701455 hasConcept C4937899 @default.
• W2467701455 hasConcept C501593827 @default.
• W2467701455 hasConcept C523546767 @default.
• W2467701455 hasConcept C54355233 @default.
• W2467701455 hasConcept C58123911 @default.
• W2467701455 hasConcept C86803240 @default.
• W2467701455 hasConcept C89423630 @default.
• W2467701455 hasConceptScore W2467701455C185592680 @default.
• W2467701455 hasConceptScore W2467701455C2776352461 @default.
• W2467701455 hasConceptScore W2467701455C2776460866 @default.
• W2467701455 hasConceptScore W2467701455C2777637488 @default.
• W2467701455 hasConceptScore W2467701455C2778049240 @default.
• W2467701455 hasConceptScore W2467701455C2778512257 @default.
• W2467701455 hasConceptScore W2467701455C2778836808 @default.
• W2467701455 hasConceptScore W2467701455C2778907293 @default.
• W2467701455 hasConceptScore W2467701455C2781276175 @default.
• W2467701455 hasConceptScore W2467701455C4937899 @default.
• W2467701455 hasConceptScore W2467701455C501593827 @default.
• W2467701455 hasConceptScore W2467701455C523546767 @default.
• W2467701455 hasConceptScore W2467701455C54355233 @default.
• W2467701455 hasConceptScore W2467701455C58123911 @default.
• W2467701455 hasConceptScore W2467701455C86803240 @default.
• W2467701455 hasConceptScore W2467701455C89423630 @default.

• next