FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2467821330> ?p ?o ?g. }

• W2467821330 endingPage "87" @default.
• W2467821330 startingPage "80" @default.
• W2467821330 abstract "In this work was described poly(d,l-lactide) microwave synthesis using tin(II) 2-ethylhexanoate initiated ring-opening polymerization. Polymerization was performed at 100 °C with monomer to initiator molar ratio ([M]/[I]) of 5,000 in 30 min. The achieved number average molar mass of obtained polymers (determined by gel permeation chromatography) was 102,320 g/mol, with the polydispersion index, Q, 2.80. Structural characterization was performed by FT-IR spectroscopy followed characteristic bands. For applicative purposes the obtained polymer was purified during the procedure of microsphere preparation. Biodegradable microspheres prepared from poly(d,l-lactide) have been widely studied in recent years and have become well established controlled drug delivery systems. In this work microspheres were loaded with allyl thiosulfinate (allicin) and its transforments products (ajoene and vinyldithiine), as pharmacological active substances. The morphology of the microspheres was analyzed using a scanning electron microscope. Allicin was synthesized by acid oxidation of allyl disufide and purification of obtained products by liquid–liquid extraction with diethyl ether. Obtained allicin, purity 73%, was transformed using microwave in acetone solution, at solvent boiling temperature, for 5 min. For the quality and quantity analysis of allicin and its transformation process was used LC/MS chromatography. (E)- and (Z)-ajoene were detected at retention time 3.1 and 3.3 min, respectively, whence 3-vynil-4H-1,2-dithiine and 2-vynil-4H-1,3-dithiine were detected at 4.3 and 4.8 min, respectively. Retention time of allicin was 2.93 min, according to liquid chromatography results. HPLC method was used for assessment of pharmaceutical substances (alicine and alicine transforments) releasing from microspheres at room temperature in solutions with different pH (pH = 3 and pH = 8) for 24 h." @default.
• W2467821330 created "2016-07-22" @default.
• W2467821330 creator A5015589936 @default.
• W2467821330 creator A5031773698 @default.
• W2467821330 creator A5037451262 @default.
• W2467821330 creator A5038523321 @default.
• W2467821330 creator A5045369848 @default.
• W2467821330 creator A5070296952 @default.
• W2467821330 creator A5086315941 @default.
• W2467821330 date "2011-08-03" @default.
• W2467821330 modified "2023-10-12" @default.
• W2467821330 title "Characterization and Release Kinetics of Allylthiosufinate and its Transforments from Poly(d,l-Lactide) Microspheres" @default.
• W2467821330 cites W164067098 @default.
• W2467821330 cites W1968063895 @default.
• W2467821330 cites W1979552813 @default.
• W2467821330 cites W1984172821 @default.
• W2467821330 cites W1997523899 @default.
• W2467821330 cites W1998998042 @default.
• W2467821330 cites W2010191564 @default.
• W2467821330 cites W2012304660 @default.
• W2467821330 cites W2012701231 @default.
• W2467821330 cites W2014099470 @default.
• W2467821330 cites W2014445031 @default.
• W2467821330 cites W2015500885 @default.
• W2467821330 cites W2036339102 @default.
• W2467821330 cites W2037187339 @default.
• W2467821330 cites W2038477071 @default.
• W2467821330 cites W2041007310 @default.
• W2467821330 cites W2041470308 @default.
• W2467821330 cites W2046105089 @default.
• W2467821330 cites W2052056214 @default.
• W2467821330 cites W2053251303 @default.
• W2467821330 cites W2053419263 @default.
• W2467821330 cites W2059916134 @default.
• W2467821330 cites W2061439749 @default.
• W2467821330 cites W2072588863 @default.
• W2467821330 cites W2074742324 @default.
• W2467821330 cites W2077458352 @default.
• W2467821330 cites W2085385064 @default.
• W2467821330 cites W2089022775 @default.
• W2467821330 cites W2093294080 @default.
• W2467821330 cites W2136276033 @default.
• W2467821330 cites W2157551905 @default.
• W2467821330 cites W2170569173 @default.
• W2467821330 cites W2321823447 @default.
• W2467821330 cites W2330450977 @default.
• W2467821330 cites W4232135728 @default.
• W2467821330 cites W4256528738 @default.
• W2467821330 doi "https://doi.org/10.1007/s10924-011-0337-x" @default.
• W2467821330 hasPublicationYear "2011" @default.
• W2467821330 type Work @default.
• W2467821330 sameAs 2467821330 @default.
• W2467821330 citedByCount "5" @default.
• W2467821330 countsByYear W24678213302017 @default.
• W2467821330 countsByYear W24678213302018 @default.
• W2467821330 countsByYear W24678213302019 @default.
• W2467821330 countsByYear W24678213302023 @default.
• W2467821330 crossrefType "journal-article" @default.
• W2467821330 hasAuthorship W2467821330A5015589936 @default.
• W2467821330 hasAuthorship W2467821330A5031773698 @default.
• W2467821330 hasAuthorship W2467821330A5037451262 @default.
• W2467821330 hasAuthorship W2467821330A5038523321 @default.
• W2467821330 hasAuthorship W2467821330A5045369848 @default.
• W2467821330 hasAuthorship W2467821330A5070296952 @default.
• W2467821330 hasAuthorship W2467821330A5086315941 @default.
• W2467821330 hasBestOaLocation W24678213301 @default.
• W2467821330 hasConcept C13965031 @default.
• W2467821330 hasConcept C159985019 @default.
• W2467821330 hasConcept C178790620 @default.
• W2467821330 hasConcept C179998833 @default.
• W2467821330 hasConcept C185592680 @default.
• W2467821330 hasConcept C188027245 @default.
• W2467821330 hasConcept C192562407 @default.
• W2467821330 hasConcept C196503311 @default.
• W2467821330 hasConcept C2776721371 @default.
• W2467821330 hasConcept C2776743539 @default.
• W2467821330 hasConcept C2781005338 @default.
• W2467821330 hasConcept C43617362 @default.
• W2467821330 hasConcept C44228677 @default.
• W2467821330 hasConcept C521977710 @default.
• W2467821330 hasConcept C63179538 @default.
• W2467821330 hasConceptScore W2467821330C13965031 @default.
• W2467821330 hasConceptScore W2467821330C159985019 @default.
• W2467821330 hasConceptScore W2467821330C178790620 @default.
• W2467821330 hasConceptScore W2467821330C179998833 @default.
• W2467821330 hasConceptScore W2467821330C185592680 @default.
• W2467821330 hasConceptScore W2467821330C188027245 @default.
• W2467821330 hasConceptScore W2467821330C192562407 @default.
• W2467821330 hasConceptScore W2467821330C196503311 @default.
• W2467821330 hasConceptScore W2467821330C2776721371 @default.
• W2467821330 hasConceptScore W2467821330C2776743539 @default.
• W2467821330 hasConceptScore W2467821330C2781005338 @default.
• W2467821330 hasConceptScore W2467821330C43617362 @default.
• W2467821330 hasConceptScore W2467821330C44228677 @default.
• W2467821330 hasConceptScore W2467821330C521977710 @default.
• W2467821330 hasConceptScore W2467821330C63179538 @default.
• W2467821330 hasIssue "1" @default.
• W2467821330 hasLocation W24678213301 @default.

• next