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- W2467874682 abstract "We describe the use of mass spectral analysis for the qualitative analysis of glycans. We examine the spectra from Electrospray Ionization Mass Spectrometry (ESI MS), Matrix Assisted Laser Desorption Mass Spectrometry (MALDI MS) and Atmospheric Pressure Ionization Mass Spectrometry (API MS) of carbohydrates. The former are time-of-flight (TOF) instruments and the last a triple quadrapole instrument. We have one spectrum that is a single quadrapole instrument. We describe several methods that aid in the determination of oligosaccharide structure by MS. They are: N- and O-linked oligosaccharide enzymic/borohydride N-linkage cleavage and O-linked reductive β-elimination, from glycoproteins, nonreductive β-elimination of O-linked oligosaccharides from glycoproteins, two isolation methods for nonglycoprotein oligosaccharides, sulfate/phosphate substitution discernment of oligosaccharides and the isolation method for amino acid substituted O-linked oligosaccharides from glycoproteins. We provide a partial bibliography for the possible future participation of sialyl lactose-6′ phosphate in disease treatment." @default.
- W2467874682 created "2016-07-22" @default.
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- W2467874682 date "2016-01-01" @default.
- W2467874682 modified "2023-10-17" @default.
- W2467874682 title "Mass Spectral Analysis of Carbohydrates" @default.
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- W2467874682 doi "https://doi.org/10.1016/b978-0-12-804129-1.00007-x" @default.
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