Matches in SemOpenAlex for { <https://semopenalex.org/work/W2468174310> ?p ?o ?g. }
Showing items 1 to 52 of
52
with 100 items per page.
- W2468174310 endingPage "7" @default.
- W2468174310 startingPage "1844" @default.
- W2468174310 abstract "GENERAL DATA: The clinical manifestations and neuropathological signs of multiple sclerosis have been recognized for more than one hundred years, but the cause remains unknown.Multiple sclerosis is not evenly distributed throughout the world. There is an important north-south gradient in the northern hemisphere and inversely in the southern hemisphere; multiple sclerosis is more frequent in the higher altitudes. For a given latitude, there is a difference by ethnic origin. These observations indicate that multiple sclerosis is a multifactorial condition determined by both genetic and environmental factors.Progress in our knowledge of the human genome and statistical analysis techniques have made it possible to search for genetic factors in multiple sclerosis using two complementary approaches. The first is by anonymous screening and the second is to search for a candidate gene. The HLA locus is the only one with an identified predisposing effect for multiple sclerosis. It only accounts for 10 to 20% of the genetic predisposition for multiple sclerosis and many factors remain to be discovered." @default.
- W2468174310 created "2016-07-22" @default.
- W2468174310 creator A5005476990 @default.
- W2468174310 creator A5006263039 @default.
- W2468174310 creator A5019490953 @default.
- W2468174310 creator A5024102528 @default.
- W2468174310 creator A5025893445 @default.
- W2468174310 creator A5031435116 @default.
- W2468174310 creator A5049933907 @default.
- W2468174310 date "2001-12-08" @default.
- W2468174310 modified "2023-10-18" @default.
- W2468174310 title "[Genetic factors in multiple sclerosis]." @default.
- W2468174310 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11776707" @default.
- W2468174310 hasPublicationYear "2001" @default.
- W2468174310 type Work @default.
- W2468174310 sameAs 2468174310 @default.
- W2468174310 citedByCount "1" @default.
- W2468174310 crossrefType "journal-article" @default.
- W2468174310 hasAuthorship W2468174310A5005476990 @default.
- W2468174310 hasAuthorship W2468174310A5006263039 @default.
- W2468174310 hasAuthorship W2468174310A5019490953 @default.
- W2468174310 hasAuthorship W2468174310A5024102528 @default.
- W2468174310 hasAuthorship W2468174310A5025893445 @default.
- W2468174310 hasAuthorship W2468174310A5031435116 @default.
- W2468174310 hasAuthorship W2468174310A5049933907 @default.
- W2468174310 hasConcept C104317684 @default.
- W2468174310 hasConcept C138885662 @default.
- W2468174310 hasConcept C15708023 @default.
- W2468174310 hasConcept C29456083 @default.
- W2468174310 hasConcept C2993266883 @default.
- W2468174310 hasConcept C54355233 @default.
- W2468174310 hasConcept C71924100 @default.
- W2468174310 hasConcept C86803240 @default.
- W2468174310 hasConceptScore W2468174310C104317684 @default.
- W2468174310 hasConceptScore W2468174310C138885662 @default.
- W2468174310 hasConceptScore W2468174310C15708023 @default.
- W2468174310 hasConceptScore W2468174310C29456083 @default.
- W2468174310 hasConceptScore W2468174310C2993266883 @default.
- W2468174310 hasConceptScore W2468174310C54355233 @default.
- W2468174310 hasConceptScore W2468174310C71924100 @default.
- W2468174310 hasConceptScore W2468174310C86803240 @default.
- W2468174310 hasIssue "37" @default.
- W2468174310 hasLocation W24681743101 @default.
- W2468174310 hasOpenAccess W2468174310 @default.
- W2468174310 hasPrimaryLocation W24681743101 @default.
- W2468174310 hasVolume "30" @default.
- W2468174310 isParatext "false" @default.
- W2468174310 isRetracted "false" @default.
- W2468174310 magId "2468174310" @default.
- W2468174310 workType "article" @default.