FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2468180023> ?p ?o ?g. }

• W2468180023 endingPage "5754" @default.
• W2468180023 startingPage "5741" @default.
• W2468180023 abstract "Recently, ultrasonic imaging of soft tissue mechanics has been increasingly studied to image otherwise undetectable pathologies. However, many underlying mechanisms of tissue stiffening remain unknown, requiring small animal studies and adapted elasticity mapping techniques. Harmonic motion imaging (HMI) assesses tissue viscoelasticity by inducing localized oscillation from a periodic acoustic radiation force. The objective of this study was to evaluate the feasibility of HMI for in vivo elasticity mapping of abdominal organs in small animals. Pathological cases, i.e. chronic pancreatitis and pancreatic cancer, were also studied in vivo to assess the capability of HMI for detection of the change in mechanical properties. A 4.5 MHz focused ultrasound transducer (FUS) generated an amplitude-modulated beam resulting in 50 Hz harmonic tissue oscillations at its focus. Axial tissue displacement was estimated using 1D-cross-correlation of RF signals acquired with a 7.8 MHz diagnostic transducer confocally aligned with the FUS. In vitro results in canine liver and kidney showed the correlation between HMI displacement and Young's moduli measured by rheometry compression testing. HMI was capable of providing reproducible elasticity maps of the mouse abdominal region in vivo allowing the identification of, from stiffest to softest, the murine kidney, pancreas, liver, and spleen. Finally, pancreata affected by pancreatitis and pancreatic cancer showed HMI displacements 1.7 and 2.2 times lower than in the control case, respectively, indicating higher stiffness. The HMI displacement amplitude was correlated with the extent of fibrosis as well as detecting the very onset of stiffening even before fibrosis could be detected on H&E. This work shows that HMI can produce reliable elasticity maps of mouse abdominal region in vivo, thus providing a potentially critical tool to assess pathologies affecting organ elasticity." @default.
• W2468180023 created "2016-07-22" @default.
• W2468180023 creator A5000454252 @default.
• W2468180023 creator A5023251981 @default.
• W2468180023 creator A5028724731 @default.
• W2468180023 creator A5035158639 @default.
• W2468180023 creator A5064530138 @default.
• W2468180023 creator A5067749727 @default.
• W2468180023 creator A5083809253 @default.
• W2468180023 date "2016-07-12" @default.
• W2468180023 modified "2023-10-17" @default.
• W2468180023 title "Elasticity mapping of murine abdominal organs<i>in vivo</i>using harmonic motion imaging (HMI)" @default.
• W2468180023 cites W1552235434 @default.
• W2468180023 cites W1558675360 @default.
• W2468180023 cites W1600896668 @default.
• W2468180023 cites W1677634964 @default.
• W2468180023 cites W1967526953 @default.
• W2468180023 cites W1969201526 @default.
• W2468180023 cites W1972142772 @default.
• W2468180023 cites W1972702648 @default.
• W2468180023 cites W1985365374 @default.
• W2468180023 cites W1987433482 @default.
• W2468180023 cites W1992995822 @default.
• W2468180023 cites W1994686298 @default.
• W2468180023 cites W1998725911 @default.
• W2468180023 cites W2003429878 @default.
• W2468180023 cites W2006618704 @default.
• W2468180023 cites W2009135063 @default.
• W2468180023 cites W2010413546 @default.
• W2468180023 cites W2014571208 @default.
• W2468180023 cites W2022958190 @default.
• W2468180023 cites W2023243589 @default.
• W2468180023 cites W2028033341 @default.
• W2468180023 cites W2029156639 @default.
• W2468180023 cites W2030996837 @default.
• W2468180023 cites W2036604908 @default.
• W2468180023 cites W2041132613 @default.
• W2468180023 cites W2056095836 @default.
• W2468180023 cites W2058592552 @default.
• W2468180023 cites W2063244960 @default.
• W2468180023 cites W2065021138 @default.
• W2468180023 cites W2066135299 @default.
• W2468180023 cites W2068109231 @default.
• W2468180023 cites W2071307647 @default.
• W2468180023 cites W2071927715 @default.
• W2468180023 cites W2078896707 @default.
• W2468180023 cites W2083039650 @default.
• W2468180023 cites W2089776912 @default.
• W2468180023 cites W2099826407 @default.
• W2468180023 cites W2103008951 @default.
• W2468180023 cites W2103232886 @default.
• W2468180023 cites W2105730019 @default.
• W2468180023 cites W2107441200 @default.
• W2468180023 cites W2110280396 @default.
• W2468180023 cites W2122857209 @default.
• W2468180023 cites W2124322063 @default.
• W2468180023 cites W2128366104 @default.
• W2468180023 cites W2130287314 @default.
• W2468180023 cites W2130929399 @default.
• W2468180023 cites W2131872096 @default.
• W2468180023 cites W2137363797 @default.
• W2468180023 cites W2143503408 @default.
• W2468180023 cites W2150815979 @default.
• W2468180023 cites W2153025372 @default.
• W2468180023 cites W2164689751 @default.
• W2468180023 cites W2168528001 @default.
• W2468180023 cites W2169961966 @default.
• W2468180023 cites W2170552969 @default.
• W2468180023 cites W2198029412 @default.
• W2468180023 cites W2219978888 @default.
• W2468180023 cites W224155369 @default.
• W2468180023 cites W2315027900 @default.
• W2468180023 cites W2315212655 @default.
• W2468180023 cites W2325270355 @default.
• W2468180023 doi "https://doi.org/10.1088/0031-9155/61/15/5741" @default.
• W2468180023 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5048218" @default.
• W2468180023 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/27401609" @default.
• W2468180023 hasPublicationYear "2016" @default.
• W2468180023 type Work @default.
• W2468180023 sameAs 2468180023 @default.
• W2468180023 citedByCount "20" @default.
• W2468180023 countsByYear W24681800232017 @default.
• W2468180023 countsByYear W24681800232018 @default.
• W2468180023 countsByYear W24681800232019 @default.
• W2468180023 countsByYear W24681800232020 @default.
• W2468180023 countsByYear W24681800232021 @default.
• W2468180023 countsByYear W24681800232022 @default.
• W2468180023 countsByYear W24681800232023 @default.
• W2468180023 crossrefType "journal-article" @default.
• W2468180023 hasAuthorship W2468180023A5000454252 @default.
• W2468180023 hasAuthorship W2468180023A5023251981 @default.
• W2468180023 hasAuthorship W2468180023A5028724731 @default.
• W2468180023 hasAuthorship W2468180023A5035158639 @default.
• W2468180023 hasAuthorship W2468180023A5064530138 @default.
• W2468180023 hasAuthorship W2468180023A5067749727 @default.
• W2468180023 hasAuthorship W2468180023A5083809253 @default.
• W2468180023 hasBestOaLocation W24681800232 @default.
• W2468180023 hasConcept C121332964 @default.

• next