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• W2468255657 abstract "Transcriptomic methods are now widely used in functional genomic research. The vast amount of information received from these studies comes along with the challenge of developing a precise picture of the functional consequences and the characteristic regulatory mechanisms. Here we assess recent studies in marine species and their adaptation to polar (and seasonal) cold and explore how they have been able to draw reliable conclusions from transcriptomic patterns on functional consequences in the organisms. Our analysis indicates that the interpretation of transcriptomic data suffers from insufficient understanding of the consequences for whole organism performance and fitness and comes with the risk of supporting only preliminary and superficial statements. We propose that the functional understanding of transcriptomic data may be improved by their tighter integration into overarching physiological concepts that support the more specific interpretation of the ‘omics’ data and, at the same time, can be developed further through embedding the transcriptomic phenomena observed. Such possibilities have not been fully exploited. In the context of thermal adaptation and limitation, we explore preliminary evidence that the concept of oxygen and capacity limited thermal tolerance (OCLTT) may provide sufficient complexity to guide the integration of such data and the development of associated functional hypotheses. At the same time, we identify a lack of methodological approaches linking genes and function to higher levels of integration, in terms of organism and ecosystem functioning, at temporal and geographical scales, to support more reliable conclusions and be predictive with respect to the effects of global changes." @default.
• W2468255657 created "2016-07-22" @default.
• W2468255657 creator A5021048352 @default.
• W2468255657 creator A5028845660 @default.
• W2468255657 creator A5089898800 @default.
• W2468255657 date "2016-06-26" @default.
• W2468255657 modified "2023-10-18" @default.
• W2468255657 title "Integrated studies of organismal plasticity through physiological and transcriptomic approaches: examples from marine polar regions" @default.
• W2468255657 cites W1189742268 @default.
• W2468255657 cites W1512092819 @default.
• W2468255657 cites W1543291357 @default.
• W2468255657 cites W1567095048 @default.
• W2468255657 cites W1592418946 @default.
• W2468255657 cites W1901189090 @default.
• W2468255657 cites W1911154009 @default.
• W2468255657 cites W1950210429 @default.
• W2468255657 cites W1955900122 @default.
• W2468255657 cites W1963542257 @default.
• W2468255657 cites W1964371015 @default.
• W2468255657 cites W1980272949 @default.
• W2468255657 cites W1981405183 @default.
• W2468255657 cites W1982170899 @default.
• W2468255657 cites W1983505489 @default.
• W2468255657 cites W1989753020 @default.
• W2468255657 cites W1993002923 @default.
• W2468255657 cites W1996331702 @default.
• W2468255657 cites W1997786495 @default.
• W2468255657 cites W1997795942 @default.
• W2468255657 cites W2005507415 @default.
• W2468255657 cites W2006010471 @default.
• W2468255657 cites W2009714443 @default.
• W2468255657 cites W2012889126 @default.
• W2468255657 cites W2015139747 @default.
• W2468255657 cites W2026604651 @default.
• W2468255657 cites W2032881104 @default.
• W2468255657 cites W2033743423 @default.
• W2468255657 cites W2042756303 @default.
• W2468255657 cites W2048437533 @default.
• W2468255657 cites W2050303528 @default.
• W2468255657 cites W2054651001 @default.
• W2468255657 cites W2059092470 @default.
• W2468255657 cites W2060797027 @default.
• W2468255657 cites W2060842569 @default.
• W2468255657 cites W2061187674 @default.
• W2468255657 cites W2066192900 @default.
• W2468255657 cites W2068292608 @default.
• W2468255657 cites W2074984745 @default.
• W2468255657 cites W2076389425 @default.
• W2468255657 cites W2089045960 @default.
• W2468255657 cites W2089675184 @default.
• W2468255657 cites W2090322363 @default.
• W2468255657 cites W2090400710 @default.
• W2468255657 cites W2091287979 @default.
• W2468255657 cites W2101438717 @default.
• W2468255657 cites W2101996618 @default.
• W2468255657 cites W2105429491 @default.
• W2468255657 cites W2108326283 @default.
• W2468255657 cites W2112870021 @default.
• W2468255657 cites W2115358332 @default.
• W2468255657 cites W2115746516 @default.
• W2468255657 cites W2116978877 @default.
• W2468255657 cites W2118353359 @default.
• W2468255657 cites W2118538068 @default.
• W2468255657 cites W2123527774 @default.
• W2468255657 cites W2123556133 @default.
• W2468255657 cites W2127896664 @default.
• W2468255657 cites W2128395009 @default.
• W2468255657 cites W2129251357 @default.
• W2468255657 cites W2129589249 @default.
• W2468255657 cites W2129608469 @default.
• W2468255657 cites W2133659881 @default.
• W2468255657 cites W2137471016 @default.
• W2468255657 cites W2137631906 @default.
• W2468255657 cites W2142464651 @default.
• W2468255657 cites W2146484634 @default.
• W2468255657 cites W2146529249 @default.
• W2468255657 cites W2146992469 @default.
• W2468255657 cites W2147174804 @default.
• W2468255657 cites W2150809444 @default.
• W2468255657 cites W2153636218 @default.
• W2468255657 cites W2154346441 @default.
• W2468255657 cites W2163422938 @default.
• W2468255657 cites W2164387119 @default.
• W2468255657 cites W2167379927 @default.
• W2468255657 cites W2167975995 @default.
• W2468255657 cites W2173095331 @default.
• W2468255657 cites W2195184589 @default.
• W2468255657 cites W2276034717 @default.
• W2468255657 cites W2287609885 @default.
• W2468255657 cites W2950048343 @default.
• W2468255657 cites W4238465605 @default.
• W2468255657 cites W4247599257 @default.
• W2468255657 cites W4376542707 @default.
• W2468255657 cites W85713036 @default.
• W2468255657 cites W97621408 @default.
• W2468255657 cites W1972681512 @default.
• W2468255657 doi "https://doi.org/10.1093/bfgp/elw024" @default.
• W2468255657 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/27345433" @default.

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