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- W2468390047 abstract "Morphine (M), an opioid agonist, was administered to postpartum (PP) Angus cows to investigate opioid modulation of gonadotropin secretion. In Exp. 1, eight PP cows (36.9 ± 2.3 d) received either M (1 mg/kg; n = 4) or saline solution (S) (n = 4) via i.v. injection 36 h after calf removal. Morphine decreased (P < .01) the number of serum LH pulses (3.0 ± 1.1 pre- vs .3 ± .3 post-pulses/h) and, compared with pretreatment values (3.3 ng/ml), decreased (P < .05) mean LH at 105 min (2.1 ng/ml) through 270 min (1.9 ng/ml ± .4). Serum prolactin (PRL) increased (P < .01) following M from 16.4 ng/ml to a peak of 59.3 ng/ml (± 3.9). Serum FSH concentrations were unaffected. In Exp. 2, M (.31 mg/kg i.v. injection followed by .15 mg/(kg · h) infusion; n = 6) or S (n = 6) treatments were given for 7 h beginning 36 h after calf removal. Serum LH was similar between groups during the pretreatment and the first 6 h of infusion, but M decreased (P < .001) the number of serum LH pulses (.44 ± .09 vs .06 ± .04 pulses/h). Morphine increased (P < .05) serum PRL. It is concluded that M differentially modulated gonadotropin secretion in the cow such that PRL increased, LH decreased and FSH was unchanged." @default.
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- W2468390047 date "1988-01-01" @default.
- W2468390047 modified "2023-10-17" @default.
- W2468390047 title "Effect of Morphine on Serum Gonadotropin Concentrations in Postpartum Beef Cows" @default.
- W2468390047 doi "https://doi.org/10.2527/jas1988.66112930x" @default.
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