Matches in SemOpenAlex for { <https://semopenalex.org/work/W2468405244> ?p ?o ?g. }
Showing items 1 to 59 of
59
with 100 items per page.
- W2468405244 endingPage "196" @default.
- W2468405244 startingPage "196" @default.
- W2468405244 abstract "Background The anterior approach for total hip arthroplasty has recently been hypothesized to result in less muscle damage. While clinical outcome studies are essential, they are subject to patient and surgeon bias. We prospectively analyzed biochemical markers of muscle damage and inflammation in patients receiving anterior and posterior minimally-invasive total hip arthroplasty to provide objective evidence of the surgical insult. Methods 29 patients receiving an anterior and 28 patients receiving a posterior total hip arthroplasty were analyzed. Peri-operative and radiographic data were collected to ensure similar cohorts. Creatine kinase, C-reactive protein, Interleukin-6, Interleukin-1beta, and Tumor necrosis factor-alpha were collected pre-operatively, post-operatively, and on post-operative days 1 and 2. Comparisons between the groups were made using the Student9s t-test and Fisher9s Exact test. Independent predictors of elevation in markers of inflammation and muscle damage were determined using multivariate logistic regression analysis. Results Markers of inflammation were slightly decreased in direct anterior group (mean differences in C-reactive protein 27.5 [95% confidence interval −24.7–79.6] mg/dL, Interleukin-6 13.5 [95% confidence interval −11.5–38.4] pg/ml, Interleukin-1beta 42.6 [95% confidence interval −10.4–95.6], and Tumor necrosis factor-alpha 148.6 [95% confidence interval −69.3–366.6] pg/ml). The rise in creatine kinase was 5.5 times higher in the post anesthesia care unit (mean difference 150.3 [95% confidence interval 70.4–230.2] units/L, p Conclusion Anterior total hip arthroplasty caused significantly less muscle damage compared to traditional posterior surgery as indicated by creatine kinase levels. The clinical importance of this rise needs to be delineated by further clinical studies. The overall physiologic burden as measured by markers of inflammation, however, appears to be similar. Objective measurement of muscle damage and inflammation provides an unbiased way of determining the immediate effects of surgical intervention in total hip arthroplasty patients." @default.
- W2468405244 created "2016-07-22" @default.
- W2468405244 creator A5046400467 @default.
- W2468405244 date "2012-09-01" @default.
- W2468405244 modified "2023-09-26" @default.
- W2468405244 title "A Prospective Comparison of Minimally Invasive Direct Anterior Versus Posterior Total Hip Based Upon Inflammation and Muscle Damage Markers" @default.
- W2468405244 hasPublicationYear "2012" @default.
- W2468405244 type Work @default.
- W2468405244 sameAs 2468405244 @default.
- W2468405244 citedByCount "0" @default.
- W2468405244 crossrefType "journal-article" @default.
- W2468405244 hasAuthorship W2468405244A5046400467 @default.
- W2468405244 hasConcept C126322002 @default.
- W2468405244 hasConcept C141071460 @default.
- W2468405244 hasConcept C156957248 @default.
- W2468405244 hasConcept C188816634 @default.
- W2468405244 hasConcept C2776914184 @default.
- W2468405244 hasConcept C36880943 @default.
- W2468405244 hasConcept C44249647 @default.
- W2468405244 hasConcept C71924100 @default.
- W2468405244 hasConcept C90924648 @default.
- W2468405244 hasConceptScore W2468405244C126322002 @default.
- W2468405244 hasConceptScore W2468405244C141071460 @default.
- W2468405244 hasConceptScore W2468405244C156957248 @default.
- W2468405244 hasConceptScore W2468405244C188816634 @default.
- W2468405244 hasConceptScore W2468405244C2776914184 @default.
- W2468405244 hasConceptScore W2468405244C36880943 @default.
- W2468405244 hasConceptScore W2468405244C44249647 @default.
- W2468405244 hasConceptScore W2468405244C71924100 @default.
- W2468405244 hasConceptScore W2468405244C90924648 @default.
- W2468405244 hasLocation W24684052441 @default.
- W2468405244 hasOpenAccess W2468405244 @default.
- W2468405244 hasPrimaryLocation W24684052441 @default.
- W2468405244 hasRelatedWork W1556537095 @default.
- W2468405244 hasRelatedWork W1980316398 @default.
- W2468405244 hasRelatedWork W2006026461 @default.
- W2468405244 hasRelatedWork W2135307973 @default.
- W2468405244 hasRelatedWork W2151756317 @default.
- W2468405244 hasRelatedWork W2239337185 @default.
- W2468405244 hasRelatedWork W2337737349 @default.
- W2468405244 hasRelatedWork W2526520147 @default.
- W2468405244 hasRelatedWork W2531378496 @default.
- W2468405244 hasRelatedWork W2888637379 @default.
- W2468405244 hasRelatedWork W2919035880 @default.
- W2468405244 hasRelatedWork W2924840694 @default.
- W2468405244 hasRelatedWork W2951653204 @default.
- W2468405244 hasRelatedWork W3006961534 @default.
- W2468405244 hasRelatedWork W3035558845 @default.
- W2468405244 hasRelatedWork W3035918961 @default.
- W2468405244 hasRelatedWork W3092397613 @default.
- W2468405244 hasRelatedWork W3126685614 @default.
- W2468405244 hasRelatedWork W2286335385 @default.
- W2468405244 hasRelatedWork W2604146395 @default.
- W2468405244 isParatext "false" @default.
- W2468405244 isRetracted "false" @default.
- W2468405244 magId "2468405244" @default.
- W2468405244 workType "article" @default.