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• W2468546038 abstract "The recombinant whole-cell mediated biooxygenation of various quinolines and isoquinolines was investigated employing three different dioxygenases of bacterial origin. Substrate screening focused on the biotransformation of cyano-substituted azaarenes, in particular. Efficiently accepted substrates were submitted to scale-up of the enzyme mediated reaction to preparative scale. The regio- and stereoselectivity of the obtained metabolites was established by NMR and X-ray diffraction after appropriate derivatization." @default.
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• W2468546038 date "2016-11-01" @default.
• W2468546038 modified "2023-10-14" @default.
• W2468546038 title "Biodihydroxylation of substituted quinolines and isoquinolines by recombinant whole-cell mediated biotransformations" @default.
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• W2468546038 doi "https://doi.org/10.1016/j.tet.2016.06.077" @default.
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