Matches in SemOpenAlex for { <https://semopenalex.org/work/W2468717962> ?p ?o ?g. }
Showing items 1 to 82 of
82
with 100 items per page.
- W2468717962 endingPage "68" @default.
- W2468717962 startingPage "59" @default.
- W2468717962 abstract "It has long been suggested that malignant melanomas, cutaneous as well as uveal, are responsive to human immune-mediated host defenses. We report here 5 consecutive cases of posterior choroidal melanomas which were treated with hyperthermia generated by high-intensity focused ultrasound. Patient immune function was monitored by determination of T-cell helper/suppressor (CD4/CD8) ratios immediately before and approximately 1 week following hyperthermia treatment. All 5 patients had normal total T-cell counts as measured by the pan-T-cell marker CD3. Two patients were noted to have inverted CD4/CD8 ratios (< 1:1) before hyperthermia. In both these cases, the ratio reverted to normal (> 1:1) 1 week following treatment. One patient whose CD4/CD8 ratio was not inverted was noted to have a further increase in his CD4 T cells relative to his CD8 (37% increase). Two patients with initially normal CD4/CD8 demonstrated no significant change following hyperthermia. It appears that ultrasonic hyperthermia may induce a systemic immunomodulatory effect in patients with posterior choroidal melanoma and inverted T-cell helper/suppressor resulting in a normalization of T-cell subset ratios." @default.
- W2468717962 created "2016-07-22" @default.
- W2468717962 creator A5014922832 @default.
- W2468717962 creator A5015607070 @default.
- W2468717962 creator A5028417543 @default.
- W2468717962 creator A5075625412 @default.
- W2468717962 creator A5083548961 @default.
- W2468717962 creator A5086809037 @default.
- W2468717962 date "1994-01-01" @default.
- W2468717962 modified "2023-10-18" @default.
- W2468717962 title "Immunomodulation in choroidal melanoma: reversal of inverted CD4/CD8 ratios following treatment with ultrasonic hyperthermia." @default.
- W2468717962 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/7703833" @default.
- W2468717962 hasPublicationYear "1994" @default.
- W2468717962 type Work @default.
- W2468717962 sameAs 2468717962 @default.
- W2468717962 citedByCount "20" @default.
- W2468717962 countsByYear W24687179622013 @default.
- W2468717962 countsByYear W24687179622015 @default.
- W2468717962 countsByYear W24687179622016 @default.
- W2468717962 countsByYear W24687179622017 @default.
- W2468717962 countsByYear W24687179622019 @default.
- W2468717962 countsByYear W24687179622022 @default.
- W2468717962 crossrefType "journal-article" @default.
- W2468717962 hasAuthorship W2468717962A5014922832 @default.
- W2468717962 hasAuthorship W2468717962A5015607070 @default.
- W2468717962 hasAuthorship W2468717962A5028417543 @default.
- W2468717962 hasAuthorship W2468717962A5075625412 @default.
- W2468717962 hasAuthorship W2468717962A5083548961 @default.
- W2468717962 hasAuthorship W2468717962A5086809037 @default.
- W2468717962 hasConcept C114684123 @default.
- W2468717962 hasConcept C126322002 @default.
- W2468717962 hasConcept C142724271 @default.
- W2468717962 hasConcept C154317977 @default.
- W2468717962 hasConcept C167672396 @default.
- W2468717962 hasConcept C185592680 @default.
- W2468717962 hasConcept C202751555 @default.
- W2468717962 hasConcept C203014093 @default.
- W2468717962 hasConcept C2776090121 @default.
- W2468717962 hasConcept C2777658100 @default.
- W2468717962 hasConcept C2779949491 @default.
- W2468717962 hasConcept C3019556204 @default.
- W2468717962 hasConcept C502942594 @default.
- W2468717962 hasConcept C55493867 @default.
- W2468717962 hasConcept C71924100 @default.
- W2468717962 hasConcept C8891405 @default.
- W2468717962 hasConceptScore W2468717962C114684123 @default.
- W2468717962 hasConceptScore W2468717962C126322002 @default.
- W2468717962 hasConceptScore W2468717962C142724271 @default.
- W2468717962 hasConceptScore W2468717962C154317977 @default.
- W2468717962 hasConceptScore W2468717962C167672396 @default.
- W2468717962 hasConceptScore W2468717962C185592680 @default.
- W2468717962 hasConceptScore W2468717962C202751555 @default.
- W2468717962 hasConceptScore W2468717962C203014093 @default.
- W2468717962 hasConceptScore W2468717962C2776090121 @default.
- W2468717962 hasConceptScore W2468717962C2777658100 @default.
- W2468717962 hasConceptScore W2468717962C2779949491 @default.
- W2468717962 hasConceptScore W2468717962C3019556204 @default.
- W2468717962 hasConceptScore W2468717962C502942594 @default.
- W2468717962 hasConceptScore W2468717962C55493867 @default.
- W2468717962 hasConceptScore W2468717962C71924100 @default.
- W2468717962 hasConceptScore W2468717962C8891405 @default.
- W2468717962 hasIssue "1-2" @default.
- W2468717962 hasLocation W24687179621 @default.
- W2468717962 hasOpenAccess W2468717962 @default.
- W2468717962 hasPrimaryLocation W24687179621 @default.
- W2468717962 hasRelatedWork W1488028176 @default.
- W2468717962 hasRelatedWork W1552542233 @default.
- W2468717962 hasRelatedWork W2323765194 @default.
- W2468717962 hasRelatedWork W2348329814 @default.
- W2468717962 hasRelatedWork W2359198796 @default.
- W2468717962 hasRelatedWork W2376606906 @default.
- W2468717962 hasRelatedWork W2468717962 @default.
- W2468717962 hasRelatedWork W2821255169 @default.
- W2468717962 hasRelatedWork W3148850623 @default.
- W2468717962 hasRelatedWork W4200336215 @default.
- W2468717962 hasVolume "5" @default.
- W2468717962 isParatext "false" @default.
- W2468717962 isRetracted "false" @default.
- W2468717962 magId "2468717962" @default.
- W2468717962 workType "article" @default.