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- W2469309917 abstract "The tissue culture of multicellular spheroids from the renal epithelial cell line LLC-PK1 (proximal tubule) is described. This represents a biological system of intermediate complexity between renal tissue in vivo and simple monolayer cultures. The multicellular structures, which show many similarities to kidney tubules in vivo, including a vectorial water transport, should prove useful for studying the potential nephrotoxicity of drugs and chemicals in vitro. In addition, the propagation of renal epithelial cells as multicellular spheroids in serum-free culture may provide information on the release of specific biological parameters, which may be suppressed or masked in serum-supplemented media." @default.
- W2469309917 created "2016-07-22" @default.
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- W2469309917 date "1993-04-01" @default.
- W2469309917 modified "2023-09-28" @default.
- W2469309917 title "Three-dimensional Growth of Renal Epithelial Cells inVitro:A Tool in Toxicity Testing" @default.
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- W2469309917 doi "https://doi.org/10.1177/026119299302100212" @default.
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