Matches in SemOpenAlex for { <https://semopenalex.org/work/W2469909862> ?p ?o ?g. }
Showing items 1 to 88 of
88
with 100 items per page.
- W2469909862 endingPage "397" @default.
- W2469909862 startingPage "391" @default.
- W2469909862 abstract "Five healthy volunteers took part in a crossover study which examined the serum concentrations of dothiepin and northiaden after a 25 mg three times a day and a 75 mg once a day dosage regimen of Prothiaden. The inter-individual variation of serum levels was large after either schedule which is to be expected with this group of drugs. The minimum steady-state level of dothiepin tended to be lower after the single daily dose, but the differences were small and not statistically significant. The approximate maximum steady-state levels of dothiepin showed large intra- and inter-subject variation and no obvious trend. The values of the desmethylated metabolite, northiaden, tended to follow the dothiepin concentrations but were lower than the parent drug. Average steady-state levels tended, with one exception, to be very similar after both regimens with no evidence of any trend when comparing the two regimens. The study showed that the two regimens yielded similar steady-state serum concentrations both of drug and metabolite but inter-individual differences were large." @default.
- W2469909862 created "2016-07-22" @default.
- W2469909862 creator A5002583936 @default.
- W2469909862 creator A5037736208 @default.
- W2469909862 creator A5049936011 @default.
- W2469909862 date "1973-01-01" @default.
- W2469909862 modified "2023-09-27" @default.
- W2469909862 title "Steady-State Serum Concentrations of Dothiepin and Northiaden after Two Dosage Regimens of Dothiepin Hydrochloride (Prothiaden)" @default.
- W2469909862 cites W1900629557 @default.
- W2469909862 cites W1984518347 @default.
- W2469909862 cites W1988401639 @default.
- W2469909862 cites W1990919641 @default.
- W2469909862 cites W2011347952 @default.
- W2469909862 cites W2018818734 @default.
- W2469909862 cites W2055123167 @default.
- W2469909862 cites W2058766187 @default.
- W2469909862 cites W2062547877 @default.
- W2469909862 cites W2071616470 @default.
- W2469909862 cites W2113836648 @default.
- W2469909862 cites W2158179124 @default.
- W2469909862 cites W2413605517 @default.
- W2469909862 cites W1965398742 @default.
- W2469909862 doi "https://doi.org/10.1177/030006057300100202" @default.
- W2469909862 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/590597" @default.
- W2469909862 hasPublicationYear "1973" @default.
- W2469909862 type Work @default.
- W2469909862 sameAs 2469909862 @default.
- W2469909862 citedByCount "2" @default.
- W2469909862 crossrefType "journal-article" @default.
- W2469909862 hasAuthorship W2469909862A5002583936 @default.
- W2469909862 hasAuthorship W2469909862A5037736208 @default.
- W2469909862 hasAuthorship W2469909862A5049936011 @default.
- W2469909862 hasConcept C112705442 @default.
- W2469909862 hasConcept C126322002 @default.
- W2469909862 hasConcept C140793950 @default.
- W2469909862 hasConcept C142724271 @default.
- W2469909862 hasConcept C147789679 @default.
- W2469909862 hasConcept C185592680 @default.
- W2469909862 hasConcept C204787440 @default.
- W2469909862 hasConcept C27081682 @default.
- W2469909862 hasConcept C2777477808 @default.
- W2469909862 hasConcept C2780035454 @default.
- W2469909862 hasConcept C2781413609 @default.
- W2469909862 hasConcept C3020081911 @default.
- W2469909862 hasConcept C71924100 @default.
- W2469909862 hasConcept C8171440 @default.
- W2469909862 hasConcept C86803240 @default.
- W2469909862 hasConcept C87813604 @default.
- W2469909862 hasConcept C98274493 @default.
- W2469909862 hasConceptScore W2469909862C112705442 @default.
- W2469909862 hasConceptScore W2469909862C126322002 @default.
- W2469909862 hasConceptScore W2469909862C140793950 @default.
- W2469909862 hasConceptScore W2469909862C142724271 @default.
- W2469909862 hasConceptScore W2469909862C147789679 @default.
- W2469909862 hasConceptScore W2469909862C185592680 @default.
- W2469909862 hasConceptScore W2469909862C204787440 @default.
- W2469909862 hasConceptScore W2469909862C27081682 @default.
- W2469909862 hasConceptScore W2469909862C2777477808 @default.
- W2469909862 hasConceptScore W2469909862C2780035454 @default.
- W2469909862 hasConceptScore W2469909862C2781413609 @default.
- W2469909862 hasConceptScore W2469909862C3020081911 @default.
- W2469909862 hasConceptScore W2469909862C71924100 @default.
- W2469909862 hasConceptScore W2469909862C8171440 @default.
- W2469909862 hasConceptScore W2469909862C86803240 @default.
- W2469909862 hasConceptScore W2469909862C87813604 @default.
- W2469909862 hasConceptScore W2469909862C98274493 @default.
- W2469909862 hasIssue "2" @default.
- W2469909862 hasLocation W24699098621 @default.
- W2469909862 hasLocation W24699098622 @default.
- W2469909862 hasOpenAccess W2469909862 @default.
- W2469909862 hasPrimaryLocation W24699098621 @default.
- W2469909862 hasRelatedWork W105896576 @default.
- W2469909862 hasRelatedWork W1492229869 @default.
- W2469909862 hasRelatedWork W1984317973 @default.
- W2469909862 hasRelatedWork W1998356222 @default.
- W2469909862 hasRelatedWork W2056938528 @default.
- W2469909862 hasRelatedWork W2132691174 @default.
- W2469909862 hasRelatedWork W2334118252 @default.
- W2469909862 hasRelatedWork W2469909862 @default.
- W2469909862 hasRelatedWork W2900112275 @default.
- W2469909862 hasRelatedWork W4298423389 @default.
- W2469909862 hasVolume "1" @default.
- W2469909862 isParatext "false" @default.
- W2469909862 isRetracted "false" @default.
- W2469909862 magId "2469909862" @default.
- W2469909862 workType "article" @default.