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- W2469988808 abstract "Six unusual matrine-type alkaloid dimers, flavesines A–F (1–6, respectively), together with three proposed biosynthetic intermediates (7–9) were isolated from the roots of Sophora flavescens. Compounds 1–5 were the first natural matrine-type alkaloid dimers, and compound 6 represented an unprecedented dimerization pattern constructed by matrine and (−)-cytisine. Their structures were elucidated by NMR, MS, single-crystal X-ray diffraction, and a chemical method. The hypothetical biogenetic pathways of 1–6 were also proposed. Compounds 1–9 exhibited inhibitory activities against hepatitis B virus." @default.
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- W2469988808 date "2016-07-08" @default.
- W2469988808 modified "2023-10-10" @default.
- W2469988808 title "Dimeric Matrine-Type Alkaloids from the Roots of <i>Sophora flavescens</i> and Their Anti-Hepatitis B Virus Activities" @default.
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- W2469988808 doi "https://doi.org/10.1021/acs.joc.6b00804" @default.
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