FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2470101280> ?p ?o ?g. }

• W2470101280 endingPage "472" @default.
• W2470101280 startingPage "466" @default.
• W2470101280 abstract "<h3>Objective:</h3> To assess the effect of patient and drug characteristics on medication adherence in people with epilepsy (PWE) in a large cohort representative of the German population. <h3>Methods:</h3> Information was obtained from the Disease Analyzer database that collects anonymous demographic and medical data from practice computer systems throughout Germany. From 2010 to 2013, adult PWE were retrospectively analyzed regarding demographic characteristics, comorbidities, and treatment with antiepileptic drugs (AED). Adherence was measured using the medication possession ratio (MPR). Individuals with an MPR <80% were classified as nonadherent. Multivariate regression models were applied to assess the association of different factors with adherence by calculating adjusted odds ratios (OR) with 95% confidence intervals. <h3>Results:</h3> A total of 31,317 PWE were included. The mean MPR was 81.1% (SD 25.7%) with 64.7% of patients showing good adherence (MPR >80%). Patient-related factors associated with good adherence to AED treatment were West German residence (OR 1.23, <i>p</i> < 0.0001) and learning disability (OR 1.80, <i>p</i> < 0.0001). Adherence was higher in patients treated with new than old (OR 1.52, <i>p</i> < 0.0001) and branded than generic AED (OR 1.44, <i>p</i> < 0.0001). Among the most common AED, levetiracetam achieved best adherence (OR 2.85, <i>p</i> < 0.0001), valproate lowest. Two or more daily dosages reduced adherence (TID vs QD: OR 0.84, <i>p</i> = 0.005; BID vs QD: OR 0.86, <i>p</i> = 0.011). <h3>Conclusions:</h3> One third of PWE treated with AED in Germany showed poor adherence, which was related to demographic characteristics and drug properties. Administration of new, well-tolerated drugs in simple dosage regimens improved AED compliance." @default.
• W2470101280 created "2016-07-22" @default.
• W2470101280 creator A5025763946 @default.
• W2470101280 creator A5026609497 @default.
• W2470101280 creator A5053278199 @default.
• W2470101280 creator A5076077497 @default.
• W2470101280 creator A5078359358 @default.
• W2470101280 creator A5086681103 @default.
• W2470101280 date "2016-07-01" @default.
• W2470101280 modified "2023-10-18" @default.
• W2470101280 title "Nonadherence to antiepileptic drugs in Germany" @default.
• W2470101280 cites W141102681 @default.
• W2470101280 cites W1966516148 @default.
• W2470101280 cites W1985845174 @default.
• W2470101280 cites W2001768305 @default.
• W2470101280 cites W2004766765 @default.
• W2470101280 cites W2004918070 @default.
• W2470101280 cites W2005680753 @default.
• W2470101280 cites W2014811670 @default.
• W2470101280 cites W2028410743 @default.
• W2470101280 cites W2030550220 @default.
• W2470101280 cites W2033122242 @default.
• W2470101280 cites W2035622774 @default.
• W2470101280 cites W2039769649 @default.
• W2470101280 cites W2044703853 @default.
• W2470101280 cites W2048355456 @default.
• W2470101280 cites W2049101004 @default.
• W2470101280 cites W2051803500 @default.
• W2470101280 cites W2053780376 @default.
• W2470101280 cites W2053816089 @default.
• W2470101280 cites W2055086381 @default.
• W2470101280 cites W2055326925 @default.
• W2470101280 cites W2058548121 @default.
• W2470101280 cites W2059101486 @default.
• W2470101280 cites W2059949457 @default.
• W2470101280 cites W2063203817 @default.
• W2470101280 cites W2063844762 @default.
• W2470101280 cites W2064985118 @default.
• W2470101280 cites W2067965966 @default.
• W2470101280 cites W2082501248 @default.
• W2470101280 cites W2093954718 @default.
• W2470101280 cites W2094677448 @default.
• W2470101280 cites W2121894908 @default.
• W2470101280 cites W2149187403 @default.
• W2470101280 cites W2149457400 @default.
• W2470101280 cites W2150087049 @default.
• W2470101280 cites W2159675003 @default.
• W2470101280 cites W2219360476 @default.
• W2470101280 doi "https://doi.org/10.1212/wnl.0000000000002791" @default.
• W2470101280 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/27371490" @default.
• W2470101280 hasPublicationYear "2016" @default.
• W2470101280 type Work @default.
• W2470101280 sameAs 2470101280 @default.
• W2470101280 citedByCount "55" @default.
• W2470101280 countsByYear W24701012802016 @default.
• W2470101280 countsByYear W24701012802017 @default.
• W2470101280 countsByYear W24701012802018 @default.
• W2470101280 countsByYear W24701012802019 @default.
• W2470101280 countsByYear W24701012802020 @default.
• W2470101280 countsByYear W24701012802021 @default.
• W2470101280 countsByYear W24701012802022 @default.
• W2470101280 countsByYear W24701012802023 @default.
• W2470101280 crossrefType "journal-article" @default.
• W2470101280 hasAuthorship W2470101280A5025763946 @default.
• W2470101280 hasAuthorship W2470101280A5026609497 @default.
• W2470101280 hasAuthorship W2470101280A5053278199 @default.
• W2470101280 hasAuthorship W2470101280A5076077497 @default.
• W2470101280 hasAuthorship W2470101280A5078359358 @default.
• W2470101280 hasAuthorship W2470101280A5086681103 @default.
• W2470101280 hasConcept C118552586 @default.
• W2470101280 hasConcept C126322002 @default.
• W2470101280 hasConcept C156957248 @default.
• W2470101280 hasConcept C187212893 @default.
• W2470101280 hasConcept C23276603 @default.
• W2470101280 hasConcept C2426938 @default.
• W2470101280 hasConcept C2777332695 @default.
• W2470101280 hasConcept C2778186239 @default.
• W2470101280 hasConcept C2994127763 @default.
• W2470101280 hasConcept C3018553135 @default.
• W2470101280 hasConcept C36434225 @default.
• W2470101280 hasConcept C44249647 @default.
• W2470101280 hasConcept C71924100 @default.
• W2470101280 hasConcept C72563966 @default.
• W2470101280 hasConcept C98274493 @default.
• W2470101280 hasConceptScore W2470101280C118552586 @default.
• W2470101280 hasConceptScore W2470101280C126322002 @default.
• W2470101280 hasConceptScore W2470101280C156957248 @default.
• W2470101280 hasConceptScore W2470101280C187212893 @default.
• W2470101280 hasConceptScore W2470101280C23276603 @default.
• W2470101280 hasConceptScore W2470101280C2426938 @default.
• W2470101280 hasConceptScore W2470101280C2777332695 @default.
• W2470101280 hasConceptScore W2470101280C2778186239 @default.
• W2470101280 hasConceptScore W2470101280C2994127763 @default.
• W2470101280 hasConceptScore W2470101280C3018553135 @default.
• W2470101280 hasConceptScore W2470101280C36434225 @default.
• W2470101280 hasConceptScore W2470101280C44249647 @default.
• W2470101280 hasConceptScore W2470101280C71924100 @default.
• W2470101280 hasConceptScore W2470101280C72563966 @default.

• next