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- W2470133963 abstract "Purpose: Although herbal medicines has been discussed for thousands of years it´s necessary experimental studies to access both usefulness and safety. Carqueja is one of the most important medicinal plants used in the treatment of multisystemic infections, but only few studies have documented adverse reactions. This study aimed to use the Carqueja in healthy dogs, within 30 days, in order to assess possible adverse effects. Methods: Eight healthy and adult Beagle dogs UNIFRAN’s experimental kennel were used as study group. A previously adaptation of 15 days was performed by the researchers to minimize stress during evaluation. It was administered 4mg/kg of Carqueja solution, twice a day, during 30 days. Animals were evaluate by clinical examination, complete blood count, alanine aminotransferase, alkaline phosphatase, albumin, total protein, urea and creatinine every 4 days during the 30 consecutive days of administration of Carqueja and 15 days after administration. Results: Partial results showed that RBCs decrease from basal to 7.9% and persisted after 15 days without Carqueja (6.6%). Monocytes were decreased 45.6% during and after treatment. In assessing biochemical the most significant change was urea, which increased 18% during treatment, but decreased to 12.9% post-administration period. Despite these alterations all of above parameters were within the reference interval for the species." @default.
- W2470133963 created "2016-07-22" @default.
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- W2470133963 date "2016-04-19" @default.
- W2470133963 modified "2023-09-23" @default.
- W2470133963 title "HEMATOLOGYCAL AND BIOCHEMICAL SERUM EVALUATION IN BEAGLE´S DOGS USING CARQUEJA (Baccharis genistelloides)" @default.
- W2470133963 doi "https://doi.org/10.26843/investigacao.v15i3.1327" @default.
- W2470133963 hasPublicationYear "2016" @default.
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