Matches in SemOpenAlex for { <https://semopenalex.org/work/W2470255576> ?p ?o ?g. }
Showing items 1 to 71 of
71
with 100 items per page.
- W2470255576 endingPage "95" @default.
- W2470255576 startingPage "87" @default.
- W2470255576 abstract "This study describes what needs to be considered in order to make a proper risk estimate of a human/animal-derived biological product from the contamination with unconventional slow virus(es). Several factors are important for this estimate. The first points regard the source of raw material (whether of human or animal origin), the kind of tissue (brain and other neural tissues being a higher risk), and in which way the tissue is collected. Then, the possibility, although remote, is taken into consideration of performing a quality control on the raw material through the measurement of PrP27-30, which is considered a specific marker of these diseases. Unfortunately, the detection of PrP27-30 is not yet so sensitive compared to the measurement of infectivity. Finally, the design of the validation experiments on the extraction and purification procedures of human/animal-derived products which gives the best estimate of safety is described. The conclusion of this study is that each biological product needs to be individually evaluated and therefore, it will be difficult to give standard guidelines for the judgement of their safety." @default.
- W2470255576 created "2016-07-22" @default.
- W2470255576 creator A5036511534 @default.
- W2470255576 date "1991-01-01" @default.
- W2470255576 modified "2023-09-24" @default.
- W2470255576 title "Methodological aspects of the validation of purification procedures of human/animal-derived products to remove unconventional slow viruses." @default.
- W2470255576 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/1794633" @default.
- W2470255576 hasPublicationYear "1991" @default.
- W2470255576 type Work @default.
- W2470255576 sameAs 2470255576 @default.
- W2470255576 citedByCount "3" @default.
- W2470255576 crossrefType "journal-article" @default.
- W2470255576 hasAuthorship W2470255576A5036511534 @default.
- W2470255576 hasConcept C111472728 @default.
- W2470255576 hasConcept C112930515 @default.
- W2470255576 hasConcept C127413603 @default.
- W2470255576 hasConcept C138885662 @default.
- W2470255576 hasConcept C17744445 @default.
- W2470255576 hasConcept C183696295 @default.
- W2470255576 hasConcept C18903297 @default.
- W2470255576 hasConcept C199539241 @default.
- W2470255576 hasConcept C2524010 @default.
- W2470255576 hasConcept C2776548248 @default.
- W2470255576 hasConcept C2779530757 @default.
- W2470255576 hasConcept C2993056352 @default.
- W2470255576 hasConcept C33923547 @default.
- W2470255576 hasConcept C41008148 @default.
- W2470255576 hasConcept C520753416 @default.
- W2470255576 hasConcept C71924100 @default.
- W2470255576 hasConcept C86803240 @default.
- W2470255576 hasConcept C90673727 @default.
- W2470255576 hasConcept C90856448 @default.
- W2470255576 hasConceptScore W2470255576C111472728 @default.
- W2470255576 hasConceptScore W2470255576C112930515 @default.
- W2470255576 hasConceptScore W2470255576C127413603 @default.
- W2470255576 hasConceptScore W2470255576C138885662 @default.
- W2470255576 hasConceptScore W2470255576C17744445 @default.
- W2470255576 hasConceptScore W2470255576C183696295 @default.
- W2470255576 hasConceptScore W2470255576C18903297 @default.
- W2470255576 hasConceptScore W2470255576C199539241 @default.
- W2470255576 hasConceptScore W2470255576C2524010 @default.
- W2470255576 hasConceptScore W2470255576C2776548248 @default.
- W2470255576 hasConceptScore W2470255576C2779530757 @default.
- W2470255576 hasConceptScore W2470255576C2993056352 @default.
- W2470255576 hasConceptScore W2470255576C33923547 @default.
- W2470255576 hasConceptScore W2470255576C41008148 @default.
- W2470255576 hasConceptScore W2470255576C520753416 @default.
- W2470255576 hasConceptScore W2470255576C71924100 @default.
- W2470255576 hasConceptScore W2470255576C86803240 @default.
- W2470255576 hasConceptScore W2470255576C90673727 @default.
- W2470255576 hasConceptScore W2470255576C90856448 @default.
- W2470255576 hasLocation W24702555761 @default.
- W2470255576 hasOpenAccess W2470255576 @default.
- W2470255576 hasPrimaryLocation W24702555761 @default.
- W2470255576 hasRelatedWork W1968483787 @default.
- W2470255576 hasRelatedWork W1972399099 @default.
- W2470255576 hasRelatedWork W1979223202 @default.
- W2470255576 hasRelatedWork W2204472172 @default.
- W2470255576 hasRelatedWork W2466983146 @default.
- W2470255576 hasRelatedWork W2470255576 @default.
- W2470255576 hasRelatedWork W2623770782 @default.
- W2470255576 hasRelatedWork W2958130028 @default.
- W2470255576 hasRelatedWork W350448290 @default.
- W2470255576 hasRelatedWork W2124633257 @default.
- W2470255576 hasVolume "75" @default.
- W2470255576 isParatext "false" @default.
- W2470255576 isRetracted "false" @default.
- W2470255576 magId "2470255576" @default.
- W2470255576 workType "article" @default.