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- W2470432390 abstract "Characterization of homoeallelic base-identity in allopolyploids is difficult since homeologous subgenomes are closely related and becomes further challenging if diploid-progenitor data is missing. We present HANDS2, a next-generation sequencing-based tool that enables highly accurate (>90%) genome-wide discovery of homeolog-specific base-identity in allopolyploids even in the absence of a diploid-progenitor. We applied HANDS2 to the transcriptomes of various cruciferous plants belonging to genus Brassica. Our results suggest that the three C genomes in Brassica are more similar to each other than the three A genomes, and provide important insights into the relationships between various Brassica tetraploids and their diploid-progenitors at a single-base resolution." @default.
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- W2470432390 date "2016-07-05" @default.
- W2470432390 modified "2023-09-27" @default.
- W2470432390 title "HANDS2: accurate assignment of homoeallelic base-identity in allopolyploids despite missing data" @default.
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- W2470432390 doi "https://doi.org/10.1038/srep29234" @default.
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