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- W2470503842 abstract "Surface-enhanced Raman scattering (SERS) has been employed to study the interaction of hepatitis B virus surface antigen (HBsAg) with mouse monoclonal antibody against HBsAg (Ab-HBsAg). SERS is used to obtain spectra of HBsAg, Ab-HBsAg and their immune complex adsorbed on colloidal silver. It is found that Ab-HBsAg is bound to silver colloids through the carboxyl groups, which are not on the antigen binding site of the Ab-HBsAg. The vibrations from tryptophan residues of the HBsAg disappear after formation of the immune complex. It is assumed that the tryptophan residues are among the antigen active sites of the HBsAg and play an important role in the interaction between Ab-HBsAg and HBsAg." @default.
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- W2470503842 date "2002-01-01" @default.
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- W2470503842 title "Surface-enhanced Raman spectroscopic study on the interaction of hepatitis B virus surface antigen and its monoclonal antibody" @default.
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