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- W2470603845 abstract "Objective To explore the biomarker of manganese exposure by analyzing the relationship between manganese exposure and concentration in some biomaterials. Methods The air samples were collected through the individual air sample. According to the manganese levels in the air, workers were assigned to control group, low concentration group and high concentration group, and manganese in the hair, urine,serum, blood cell and saliva from different group were measured respectively. The correlations between concentration of external manganese exposure and manganese concentrations in biomaterials, and years of employment and concentrations in biomaterials were analyzed. Results In the high concentration group, saliva manganese was 32.17 μg/L, hair manganese was 37.39 mg/kg, urine manganese was 2.50 μg/L, plasma manganese was 29.61 μg/L, blood manganese was 14.49 μg/L, were higher than those in the control group( 10.40μg/L, 1.60 mg/kg, 0.77 μg/L, 10.30 μg/L, 4.56 μg/L respectively )( P<0.01 ). The manganese concentration in the saliva was significantly correlated with airborne manganese concentration (r=0.649, P<0.01 ), with the years of employment (r=0.404, P<0.01 ), with the total exposure of manganese (r=0.342, P<0.01 ), with the manganese concentration of plasma (r=0.303, P<0.01) and with the manganese concentration in blood cells (r=0.359, P<0.01 ), respectively. Conclusions The concentration of manganese in saliva could work as a biomarker of manganese internal exposure.Key words: Manganese; Biological markers; Saliva" @default.
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- W2470603845 date "2010-09-01" @default.
- W2470603845 modified "2023-09-26" @default.
- W2470603845 title "Early biological markers of manganese exposure" @default.
- W2470603845 doi "https://doi.org/10.3760/cma.j.issn.1001-9391.2010.09.003" @default.
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