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• W2470639632 abstract "In Brief Objective: Ocular vestibular-evoked myogenic potentials (oVEMPs) represent extraocular muscle activity in response to vestibular stimulation. The authors sought to investigate whether posture-induced increase of the intracranial pressure (ICP) modulated oVEMP frequency tuning, that is, the amplitude ratio between 500-Hz and 1000-Hz stimuli. Design: Ten healthy subjects were enrolled in this study. The subjects were positioned in the horizontal plane (0 degree) and in a 30-degree head-downwards position to elevate the ICP. In both positions, oVEMPs were recorded using 500-Hz and 1000-Hz air-conducted tone bursts. Results: When tilting the subject from the horizontal plane to the 30-degree head-down position, oVEMP amplitudes in response to 500-Hz tone bursts distinctly decreased (3.40 μV versus 2.06 μV; p < 0.001), whereas amplitudes to 1000 Hz were only slightly diminished (2.74 μV versus 2.48 μV; p = 0.251). Correspondingly, the 500/1000-Hz amplitude ratio significantly decreased when tilting the subjects from 0- to 30-degree inclination (1.59 versus 1.05; p = 0.029). Latencies were not modulated by head-down position. Conclusions: Increasing ICP systematically alters oVEMPs in terms of absolute amplitudes and frequency tuning characteristics. oVEMPs are therefore in principle suited for noninvasive ICP monitoring. The objective of this study was to investigate whether posture-induced increase of the intracranial pressure (ICP) modulated oVEMP frequency tuning, i.e. the amplitude ratio between 500 Hz and 1000 Hz stimuli. Whentilting the subject from the horizontal plane to a 30-degree head-downwards position, oVEMP amplitudes in response to 500 Hz tone bursts distinctly decreased, whereas amplitudes to 1000 Hz were only slightlydiminished. Correspondingly, the 500/1000 Hz amplitude ratio significantly decreased. Increasing ICP systematically alters oVEMPs in terms of absolute amplitudes and frequency tuning characteristics. oVEMPs are therefore in principle suited for non-invasive ICP monitoring." @default.
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• W2470639632 date "2015-11-01" @default.
• W2470639632 modified "2023-10-11" @default.
• W2470639632 title "The Effect of Increasing Intracranial Pressure on Ocular Vestibular-Evoked Myogenic Potential Frequency Tuning" @default.
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• W2470639632 doi "https://doi.org/10.1097/aud.0000000000000190" @default.
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