Matches in SemOpenAlex for { <https://semopenalex.org/work/W2470757192> ?p ?o ?g. }
Showing items 1 to 82 of
82
with 100 items per page.
- W2470757192 endingPage "190" @default.
- W2470757192 startingPage "189" @default.
- W2470757192 abstract "Spontaneous bacterial peritonitis (SBP) is defined as an ascitic fluid infection without a surgically-treatable intra-abdominal source. Timely diagnosis and treatment of SBP may increase the patient’s survival.1 Any biological marker that could strongly predict SBP may obviate the need for paracentesis while increasing the patient’s chance of survival by expediting the diagnosis and treatment of SBP. Procalcitonin (PCT) is a marker of early infection. There is some evidence that PCT production increases only in bacterial infections. It is more sensitive and specific than CRP in differentiating bacterial infection from non-microbial inflammation.2-4 There are a few reports of the clinical utility of PCT in diagnosis of SBP in patients with cirrhosis.5-7 The aim of the present study was to determine any correlation between blood PCT and SBP in patients with cirrhosis and ascites to propose PCT test as a possible supplant for paracentesis in SBP diagnosis. We included 33 patients (15 men, 18 women; age range 16-68 years) with liver cirrhosis and ascites. They were suspected to have SBP based on the symptoms such as abdominal pain and clinical signs such as superficial abdominal tenderness. The diagnosis was established if there were more than 250 polymorphonuclear cells per milliliter of the ascitic fluid. The blood level of procalcitonin was compared between patients with and without SBP. Eight patients (24.2%) with documented SBP comprised the case group and the remaining 25 patients (75.8%) with no evidence of SBP constituted the control group. Table 1 summarizes the comparison of values between the groups with and without SBP. The percentage of patients with positive blood PCT levels was higher in case group than controls (75% vs. 8%, respectively; p=0.001). There was a significant correlation between positive blood PCT levels and the presence of SBP. The sensitivity and specificity of positive blood PCT to predict the presence of SBP were found to be 75% and 92%, respectively. Patients with hepatorenal syndrome or hepatic encephalopathy had increased levels of PCT even in the absence of SBP. Our findings showed a significant association between blood PCT and SBP diagnosis (p=0.001). A considerable proportion of cirrhotic 1. Department of Respiratory Medicine, Tehran university of Medical Sciences, Tehran, Iran 2. Department of Internal Medicine, Tehran University of Medical Sciences, Tehran, Iran 3. Department of Gastroenterology, Tehran University of Medical Sciences, Tehran, Iran 4. Department of Pathology, Tehran University of Medical Sciences, Tehran, Iran 5. Students` Scientific Research Center, Tehran University of Medical Sciences, Tehran , Iran Mehrnaz Asadi Gharabaghi1, Seyed Farshad Allameh*2, Hossein Foroutan3, Alireza Abdollahi4, Mitra Kazemi Jahromi2, Effat Kahe2, Siamak Mehdizadeh Seraj5" @default.
- W2470757192 created "2016-07-22" @default.
- W2470757192 creator A5003760647 @default.
- W2470757192 creator A5007029541 @default.
- W2470757192 creator A5038181116 @default.
- W2470757192 creator A5041714762 @default.
- W2470757192 creator A5046820867 @default.
- W2470757192 creator A5050786181 @default.
- W2470757192 creator A5069230384 @default.
- W2470757192 date "2015-01-01" @default.
- W2470757192 modified "2023-09-27" @default.
- W2470757192 title "LETTER TO THE EDITOR: BLOOD PROCALCITONIN PREDICTS SPONTANEOUS BACTERIAL PERITONITIS IN PATIENTS WITH CIRRHOSIS AND ASCITES" @default.
- W2470757192 cites W1972156650 @default.
- W2470757192 cites W2015753221 @default.
- W2470757192 cites W2016543987 @default.
- W2470757192 cites W2038142688 @default.
- W2470757192 cites W2088134521 @default.
- W2470757192 cites W2121568635 @default.
- W2470757192 cites W2403713943 @default.
- W2470757192 hasPublicationYear "2015" @default.
- W2470757192 type Work @default.
- W2470757192 sameAs 2470757192 @default.
- W2470757192 citedByCount "0" @default.
- W2470757192 crossrefType "journal-article" @default.
- W2470757192 hasAuthorship W2470757192A5003760647 @default.
- W2470757192 hasAuthorship W2470757192A5007029541 @default.
- W2470757192 hasAuthorship W2470757192A5038181116 @default.
- W2470757192 hasAuthorship W2470757192A5041714762 @default.
- W2470757192 hasAuthorship W2470757192A5046820867 @default.
- W2470757192 hasAuthorship W2470757192A5050786181 @default.
- W2470757192 hasAuthorship W2470757192A5069230384 @default.
- W2470757192 hasConcept C10936531 @default.
- W2470757192 hasConcept C126322002 @default.
- W2470757192 hasConcept C2776258039 @default.
- W2470757192 hasConcept C2777214474 @default.
- W2470757192 hasConcept C2777364826 @default.
- W2470757192 hasConcept C2778384902 @default.
- W2470757192 hasConcept C2780496750 @default.
- W2470757192 hasConcept C2780955771 @default.
- W2470757192 hasConcept C71924100 @default.
- W2470757192 hasConcept C90924648 @default.
- W2470757192 hasConceptScore W2470757192C10936531 @default.
- W2470757192 hasConceptScore W2470757192C126322002 @default.
- W2470757192 hasConceptScore W2470757192C2776258039 @default.
- W2470757192 hasConceptScore W2470757192C2777214474 @default.
- W2470757192 hasConceptScore W2470757192C2777364826 @default.
- W2470757192 hasConceptScore W2470757192C2778384902 @default.
- W2470757192 hasConceptScore W2470757192C2780496750 @default.
- W2470757192 hasConceptScore W2470757192C2780955771 @default.
- W2470757192 hasConceptScore W2470757192C71924100 @default.
- W2470757192 hasConceptScore W2470757192C90924648 @default.
- W2470757192 hasIssue "3" @default.
- W2470757192 hasLocation W24707571921 @default.
- W2470757192 hasOpenAccess W2470757192 @default.
- W2470757192 hasPrimaryLocation W24707571921 @default.
- W2470757192 hasRelatedWork W2041041118 @default.
- W2470757192 hasRelatedWork W2105608231 @default.
- W2470757192 hasRelatedWork W2145226734 @default.
- W2470757192 hasRelatedWork W2149108783 @default.
- W2470757192 hasRelatedWork W2173495480 @default.
- W2470757192 hasRelatedWork W2347641833 @default.
- W2470757192 hasRelatedWork W2353285594 @default.
- W2470757192 hasRelatedWork W2378876140 @default.
- W2470757192 hasRelatedWork W2385633473 @default.
- W2470757192 hasRelatedWork W2386017480 @default.
- W2470757192 hasRelatedWork W2390409694 @default.
- W2470757192 hasRelatedWork W2500003537 @default.
- W2470757192 hasRelatedWork W2793511522 @default.
- W2470757192 hasRelatedWork W2883752955 @default.
- W2470757192 hasRelatedWork W2884584181 @default.
- W2470757192 hasRelatedWork W2885319827 @default.
- W2470757192 hasRelatedWork W2898764537 @default.
- W2470757192 hasRelatedWork W2955364342 @default.
- W2470757192 hasRelatedWork W3029491730 @default.
- W2470757192 hasRelatedWork W3083451326 @default.
- W2470757192 hasVolume "7" @default.
- W2470757192 isParatext "false" @default.
- W2470757192 isRetracted "false" @default.
- W2470757192 magId "2470757192" @default.
- W2470757192 workType "letter" @default.