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- W2471265810 abstract "www.scielo.br/jaos he ability of hemostatic agents to promote bone repair has been investigated using in vitro and in vivo models but, up to now, the results are inconclusive. Objective: In this context, the aim of this study was to compare the potential of bone repair of collagen sponge with ?brin glue in a rat calvarial defect model. 0aterial and 0ethods: 'efects of � mm in diameter were created in rat calvariae and treated with either collagen sponge or ?brin glueuntreated defects were used as control. $tandweeNs, histological analysis and micro-CT-based histomorphometry were carried out and data were compared by two- way $1 O9$ followed by 6tudent-1ewman-.euls test when appropriatedp� .��� . 5esults: Three-dimensional reconstructions showed increased bone formation in defects treated with either collagen sponge or ?brin glue compared with untreated defects, which was con?rmed by the histological analysis. 0orphometric parameters indicated the progression of bone formation fromtoweeNs. $dditionally, ?brin glue displayed slightly higher bone formation rate when compared with collagen sponge. Conclusion: Our results have shown the bene?ts of using collagen sponge and ?brin glue to promote new bone formation in rat calvarial bone defects, the latter being discreetly more advantageous." @default.
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- W2471265810 date "2015-01-01" @default.
- W2471265810 modified "2023-09-26" @default.
- W2471265810 title "(IIHFWRIFROODJ HQVSRQJHDQG¿E ULQJOXHRQERQH repair" @default.
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