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• W2471330087 abstract "Back to table of contents Previous article Next article No AccessPatterns of neuropsychological deficits that discriminate schizophrenic individuals from siblings and control subjectsPublished Online:1 Apr 2006https://doi.org/10.1176/jnp.5.3.294AboutSectionsView articleAbstractPDF/EPUB ToolsAdd to favoritesDownload CitationsTrack Citations ShareShare onFacebookTwitterLinked InEmail View articleAbstractPrevious research on persons with schizophrenia and their relatives suggests two independent etiologic factors may combine to produce schizophrenia, and these factors may be indexed respectively by independent neuropsychological tests. Two neurocognitive measures, the Trail Making and Wisconsin Card Sorting (WCST) tests, were administered to 28 schizophrenic subjects, 15 nonschizophrenic siblings, and 35 control subjects by investigators blind to DSM-III-R diagnoses. Results support key predictions of a two-factor model: 1) having poor scores on both tests discriminated schizophrenic individuals from both siblings and control subjects, and 2) poor Trail Making and WCST performance were inversely associated among schizophrenic individuals' non- schizophrenic siblings. Access content To read the fulltext, please use one of the options below to sign in or purchase access. Personal login Institutional Login Sign in via OpenAthens Purchase Save for later Item saved, go to cart PPV Articles - Journal of Neuropsychiatry and Clinical Neurosciences $35.00 Add to cart PPV Articles - Journal of Neuropsychiatry and Clinical Neurosciences Checkout Please login/register if you wish to pair your device and check access availability. Not a subscriber? Subscribe Now / Learn More PsychiatryOnline subscription options offer access to the DSM-5 library, books, journals, CME, and patient resources. This all-in-one virtual library provides psychiatrists and mental health professionals with key resources for diagnosis, treatment, research, and professional development. Need more help? PsychiatryOnline Customer Service may be reached by emailing [email protected] or by calling 800-368-5777 (in the U.S.) or 703-907-7322 (outside the U.S.). FiguresReferencesCited byDetailsCited ByObstetric complications and cognition in schizophrenia: a systematic review and meta-analysis18 August 2022 | Psychological Medicine, Vol. 5Genetics of Psychiatric DisordersAsian Journal of Psychiatry, Vol. 4, No. 2European Archives of Psychiatry and Clinical Neuroscience, Vol. 259, No. 8Genetics of Psychiatric DisordersExecutive deficits in psychotic and bipolar disorders – Implications for our understanding of schizoaffective disorder16 April 2020 | European Psychiatry, Vol. 23, No. 1Schizophrenia Research, Vol. 89, No. 1-3Schizophrenia Bulletin, Vol. 34, No. 4NeuroRX, Vol. 3, No. 1Psychiatry Research, Vol. 144, No. 2-3Genetic bases for endophenotypes in psychiatric disorders1 April 2022 | Dialogues in Clinical Neuroscience, Vol. 7, No. 2American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, Vol. 133B, No. 1Schizophrenia Research, Vol. 71, No. 2-3Psychiatry Research, Vol. 110, No. 2Psychiatry and Clinical Neurosciences, Vol. 56, No. 4Biological Psychiatry, Vol. 50, No. 2Biological Psychiatry, Vol. 50, No. 11fMRI during affect discrimination in bipolar affective disorder4 November 2002 | Bipolar Disorders, Vol. 2, No. 3p2Psychiatry Research, Vol. 95, No. 2Cognitive Neuropsychiatry, Vol. 5, No. 3Psychiatry Research, Vol. 87, No. 2-3Schizophrenia Research, Vol. 35, No. 2Association of neuropsychological vulnerability markers in relatives of schizophrenic patientsSchizophrenia Research, Vol. 31, No. 2-3Biological Psychiatry, Vol. 44, No. 10Biological Psychiatry, Vol. 42, No. 9Schizophrenia Research, Vol. 23, No. 2Schizophrenia Research, Vol. 25, No. 1Schizophrenia Research, Vol. 26, No. 2-3Analysis of the attention deficit in schizophrenia: A study of patients and their relatives in IrelandJournal of Psychiatric Research, Vol. 29, No. 1Schizophrenia Research, Vol. 17, No. 1 Volume 5Issue 3 August 1993Pages 294-300 Metrics PDF download History Published online 1 April 2006 Published in print 1 August 1993" @default.
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