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- W2471336021 abstract "Cancer is a multistep phenomenon and multiple genetic lesions are involved in the emergence of the cancerous lesion. This has best been demonstrated in colonic cancer. The authors review their work and that of others highlighting what is known about thyroid cancer. They implicate ras mutations predominantly in follicular carcinoma, rearrangement of the ret proto-oncogene in papillary carcinoma and the tumor suppressor genes p53 and retinoblastoma gene product in all stages of thyroid carcinoma. They find a low rate of ret proto-oncogene rearrangement in the Saudi population (>5%) as compared to elsewhere in the world (20%). They find TSH receptor message abundance to be predictive of prognosis in thyroid cancer patients. Lastly, they examine whether the abundance of the anti-metastatic gene nm23 message abundance negatively correlated with the tendency of thyroid tumors to metastasize and find that not to be the case in thyroid carcinoma. The study of oncogenes and tumor suppressor genes in the pathogenesis of thyroid cancer is in its infancy; however, rapid progress is being made in identifying genes participating in malignant thyroid cell transformation." @default.
- W2471336021 created "2016-07-22" @default.
- W2471336021 creator A5042736388 @default.
- W2471336021 date "1995-05-01" @default.
- W2471336021 modified "2023-09-24" @default.
- W2471336021 title "Towards Understanding the Molecular Basis of Thyroid Cancer" @default.
- W2471336021 cites W101106793 @default.
- W2471336021 cites W128302075 @default.
- W2471336021 cites W14762771 @default.
- W2471336021 cites W1499010498 @default.
- W2471336021 cites W150182137 @default.
- W2471336021 cites W1580560855 @default.
- W2471336021 cites W1601292601 @default.
- W2471336021 cites W1606316894 @default.
- W2471336021 cites W1795641679 @default.
- W2471336021 cites W1799131074 @default.
- W2471336021 cites W1859397449 @default.
- W2471336021 cites W190015672 @default.
- W2471336021 cites W1952836109 @default.
- W2471336021 cites W1965913827 @default.
- W2471336021 cites W1966384938 @default.
- W2471336021 cites W1966552709 @default.
- W2471336021 cites W1967092942 @default.
- W2471336021 cites W1967487654 @default.
- W2471336021 cites W1967629365 @default.
- W2471336021 cites W1969229561 @default.
- W2471336021 cites W1970725961 @default.
- W2471336021 cites W1971313867 @default.
- W2471336021 cites W1971359452 @default.
- W2471336021 cites W1972946022 @default.
- W2471336021 cites W1973362991 @default.
- W2471336021 cites W1973613428 @default.
- W2471336021 cites W1973637263 @default.
- W2471336021 cites W1974252698 @default.
- W2471336021 cites W1974513412 @default.
- W2471336021 cites W1974549161 @default.
- W2471336021 cites W1974773169 @default.
- W2471336021 cites W1974933885 @default.
- W2471336021 cites W1975237867 @default.
- W2471336021 cites W1977442544 @default.
- W2471336021 cites W1977598234 @default.
- W2471336021 cites W1979892773 @default.
- W2471336021 cites W1980166477 @default.
- W2471336021 cites W1980847511 @default.
- W2471336021 cites W1980890490 @default.
- W2471336021 cites W1982061874 @default.
- W2471336021 cites W1982395246 @default.
- W2471336021 cites W1982473669 @default.
- W2471336021 cites W1982628082 @default.
- W2471336021 cites W1982745900 @default.
- W2471336021 cites W1983009417 @default.
- W2471336021 cites W1983680839 @default.
- W2471336021 cites W1985822867 @default.
- W2471336021 cites W1986179131 @default.
- W2471336021 cites W1986383101 @default.
- W2471336021 cites W1986642553 @default.
- W2471336021 cites W1988433137 @default.
- W2471336021 cites W1988897856 @default.
- W2471336021 cites W1989976890 @default.
- W2471336021 cites W1990401009 @default.
- W2471336021 cites W1990454766 @default.
- W2471336021 cites W1991121868 @default.
- W2471336021 cites W1992148801 @default.
- W2471336021 cites W1995095999 @default.
- W2471336021 cites W1995136152 @default.
- W2471336021 cites W1995237215 @default.
- W2471336021 cites W1996449685 @default.
- W2471336021 cites W1996959599 @default.
- W2471336021 cites W1999275729 @default.
- W2471336021 cites W1999510791 @default.
- W2471336021 cites W1999876280 @default.
- W2471336021 cites W2000129834 @default.
- W2471336021 cites W2000474123 @default.
- W2471336021 cites W2000646975 @default.
- W2471336021 cites W2000965640 @default.
- W2471336021 cites W2001013796 @default.
- W2471336021 cites W2001258296 @default.
- W2471336021 cites W2002623358 @default.
- W2471336021 cites W2002940582 @default.
- W2471336021 cites W2003818827 @default.
- W2471336021 cites W2005542290 @default.
- W2471336021 cites W2005873815 @default.
- W2471336021 cites W2006513743 @default.
- W2471336021 cites W2006966528 @default.
- W2471336021 cites W2007590517 @default.
- W2471336021 cites W2007599495 @default.
- W2471336021 cites W2008301561 @default.
- W2471336021 cites W2008852784 @default.
- W2471336021 cites W2009183764 @default.
- W2471336021 cites W2009395264 @default.
- W2471336021 cites W2009603041 @default.
- W2471336021 cites W2010618512 @default.
- W2471336021 cites W2011592069 @default.
- W2471336021 cites W2012141473 @default.
- W2471336021 cites W2012330736 @default.
- W2471336021 cites W2012391314 @default.
- W2471336021 cites W2012533550 @default.
- W2471336021 cites W2017599618 @default.