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• W2471586261 abstract "Abstract Purpose To evaluate the impacts of different leaf-width of multileaf collimator (MLC) on the fixed-beam intensity-modulated radiotherapy (IMRT) planning for prostate cancer patients with intermediate risk factors. Materials and methods Sixteen prostate cancer patients with intermediate risk factors were retrospectively recruited. For each patient, the two IMRT plans using MLC leaf width of 10 mm and 4 mm (sIMRT and mIMRT) were compared. All of plans were generated with the same setup and optimized parameters and methods. Homogeneity index (HI), conformity index (CI), dose distribution for planning tumor volume (PTV) and organs at risk (OARs) were analyzed to evaluate the quality of the plans. Delivery time (DT), monitor units (MUs) and control points (CPs) were used to assess the efficiency of treatment. Results For the target dose distribution, the mean HI values of the two plans for 16 patients are similar (sIMRT vs. mIMRT: 1.120±0.13 vs. 1.103±0.099, p>0.05). The mean CI of the mIMRT plans was significantly better than that of the sIMRT plans (sIMRT vs. mIMRT: 0.648±0.11 vs. 0.688±0.10, p Conclusions For the IMRT of the prostate cancer patients with intermediate risk factors, the plans with the narrower leaf-width MLC failed to promote the quality of plans, OARs dose sparing and the efficiency of treatment, and could only improve the conformity of the plans." @default.
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• W2471586261 date "2016-10-01" @default.
• W2471586261 modified "2023-09-23" @default.
• W2471586261 title "A dosimetric comparison of the fixed-beam IMRT plans using different leaf width of multileaf collimators for the intermediate risk prostate cancer" @default.
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• W2471586261 doi "https://doi.org/10.1016/j.radphyschem.2016.07.008" @default.
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