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- W2471645579 abstract "The expression level of the B subunit gene of cholera toxin (ctx) and E. coli heat labile toxin (ltx) is five to seven times more than that of A subunit gene. In these studies, a 80 basepair translation regulation element was found located in the structure gene of A gene of both toxin operon which consists of three translation initiation region. Site-directed mutation of the initiation codon of TIR3 resulted in the 9 time decrease of the expression of the downstream cistron which was translational coupled with A gene. The results indicated that translation from the internal of A gene and translation coupling are responsible for the differential expression level of the A and B gene of AB5 enterotoxin." @default.
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- W2471645579 date "2000-01-01" @default.
- W2471645579 modified "2023-09-23" @default.
- W2471645579 title "[A new model of translational control of gene expression in polycistron++ of AB5 entrerotoxin]." @default.
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