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- W2471920319 abstract "A new strategy for the highly enantio- and diastereoselective synthesis of 3,4-dihydrocoumarin derivatives bearing a fused pyrrolidine ring is reported. It is based on a Brønsted base catalyzed cascade reactivity between β,γ-unsaturated-α-ketophosphonates and imines (derived from various salicylaldehydes and diethyl aminomalonate). The approach can be described as a doubly annulative strategy where both the pyrrolidine moiety and the δ-lactone ring of the 3,4-dihydrocoumarin framework are constructed starting from acyclic precursors." @default.
- W2471920319 created "2016-07-22" @default.
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- W2471920319 date "2016-07-11" @default.
- W2471920319 modified "2023-10-16" @default.
- W2471920319 title "Organocatalytic Doubly Annulative Approach to 3,4-Dihydrocoumarins Bearing a Fused Pyrrolidine Scaffold" @default.
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- W2471920319 doi "https://doi.org/10.1021/acs.joc.6b00975" @default.
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