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- W2471926579 abstract "Background The prevalence of asthma and obesity has increased last years implying important economical and social consequences. A relationship between asthma severity and obesity grade has been found. Therefore, it is necessary to evaluate if obesity decline has a beneficial impact on asthma severity. Objective To evaluate the effect of obesity decline on control symptoms and asthma severity. Patients and methods Ninety-six patients with obesity and moderate chronic asthma were randomized to group A or B and were maintained for 40 days on a low calorie diet. At baseline and at the end of the study, symptoms, measurement of obesity, spirometry, inflammatory cytokines and immunoglobulin's levels were assessed. Diets' safety was evaluated based on laboratory test. Data were analyzed with Student's t test. Results After 40 days on a low calorie diet, in group A, there were significant decreases of obesity (p 100 UI/mL), symptoms and drug regimen remained unchanged. Both diets were not harmful for patients. Conclusion These results show that asthmatic obese patients maintained for 40 days on low calorie diet A, had obesity and IgE levels decrease and symptoms and asthma severity relief." @default.
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- W2471926579 date "2008-05-01" @default.
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- W2471926579 title "Clinical symptom relief in obese patients with persistent moderate asthma secondary to decreased obesity" @default.
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