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- W2472008251 abstract "We present a splenic primary mantle lymphoma in a 64 year old woman, without peripheral lymphoadenopathy and stage IV at the moment of the diagnosis. Grossly a splenic infiltration was observed. Microscopically, a nodular lymphoma of small lymphocytes proliferating around benign germinal centers makes the diagnosis. Immunohistochemically, tumoral lymphocytes expressed SIgG/kappa and CD5 (Leu-1). Markers of follicular center origin CD10 (CALLA) were negative. According to working formulation mantle-cell lymphoma is considered a lymphoma of intermediate grade of malignancy. In our case, the morphologic, immunologic, ultrastructural findings and clinical evolution were more characteristics of a low grade lymphoma that a intermediate grade of malignancy." @default.
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- W2472008251 date "1991-01-19" @default.
- W2472008251 modified "2023-09-23" @default.
- W2472008251 title "[Lymphoma of the splenic mantle. Morphologic, immunologic and ultrastructural characterization of a case]." @default.
- W2472008251 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2023478" @default.
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