FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2472016049> ?p ?o ?g. }

• W2472016049 endingPage "464" @default.
• W2472016049 startingPage "459" @default.
• W2472016049 abstract "Magnesium (Mg2+), an essential ion for cells and biological systems, is involved in a variety of cellular processes, including the formation and breakdown of microtubules. The results of a previous investigation suggested that as cells grow the intracellular Mg2+ concentration falls, thereby stimulating formation of the mitotic spindle. In the present work, we used a Mg2+-deficient Schizosaccharomyces pombe strain GA2, in which two essential membrane Mg2+ transporter genes (homologs of ALR1 and ALR2 in Saccharomyces cerevisae) were deleted, and its parental strain Sp292, to examine the extent to which low Mg2+ concentrations can affect mitotic spindle formation. The two S. pombe strains were transformed with a plasmid carrying a GFP-α2-tubulin construct to fluorescently label microtubules. Using the free Mg2+-specific fluorescent probe mag-fura-2, we confirmed that intracellular free Mg2+ levels were lower in GA2 than in the parental strain. Defects in interphase microtubule organization, a lower percentage of mitotic spindle formation and a reduced mitotic index were also observed in the GA2 strain. Although there was interphase microtubule polymerization, the lower level of mitotic spindle formation in the Mg2+-deficient strain suggested a greater requirement for Mg2+ in this phenomenon than previously thought." @default.
• W2472016049 created "2016-07-22" @default.
• W2472016049 creator A5009685925 @default.
• W2472016049 creator A5015048627 @default.
• W2472016049 date "2016-07-07" @default.
• W2472016049 modified "2023-10-16" @default.
• W2472016049 title "The effect of magnesium on mitotic spindle formation in Schizosaccharomyces pombe" @default.
• W2472016049 cites W1542758544 @default.
• W2472016049 cites W1971162911 @default.
• W2472016049 cites W1980520899 @default.
• W2472016049 cites W1989472917 @default.
• W2472016049 cites W1996024251 @default.
• W2472016049 cites W1997245611 @default.
• W2472016049 cites W1999317369 @default.
• W2472016049 cites W2002879561 @default.
• W2472016049 cites W2018278869 @default.
• W2472016049 cites W2023641728 @default.
• W2472016049 cites W2047156618 @default.
• W2472016049 cites W2056816531 @default.
• W2472016049 cites W2069006995 @default.
• W2472016049 cites W2074307550 @default.
• W2472016049 cites W2089416771 @default.
• W2472016049 cites W2090792199 @default.
• W2472016049 cites W2092834021 @default.
• W2472016049 cites W2096690121 @default.
• W2472016049 cites W2113980352 @default.
• W2472016049 cites W2141260882 @default.
• W2472016049 cites W2155062619 @default.
• W2472016049 cites W2161773548 @default.
• W2472016049 cites W2182230726 @default.
• W2472016049 cites W2194986544 @default.
• W2472016049 doi "https://doi.org/10.1590/1678-4685-gmb-2015-0239" @default.
• W2472016049 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5004833" @default.
• W2472016049 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/27560651" @default.
• W2472016049 hasPublicationYear "2016" @default.
• W2472016049 type Work @default.
• W2472016049 sameAs 2472016049 @default.
• W2472016049 citedByCount "8" @default.
• W2472016049 countsByYear W24720160492017 @default.
• W2472016049 countsByYear W24720160492019 @default.
• W2472016049 countsByYear W24720160492021 @default.
• W2472016049 countsByYear W24720160492022 @default.
• W2472016049 countsByYear W24720160492023 @default.
• W2472016049 crossrefType "journal-article" @default.
• W2472016049 hasAuthorship W2472016049A5009685925 @default.
• W2472016049 hasAuthorship W2472016049A5015048627 @default.
• W2472016049 hasBestOaLocation W24720160491 @default.
• W2472016049 hasConcept C104317684 @default.
• W2472016049 hasConcept C12554922 @default.
• W2472016049 hasConcept C1491633281 @default.
• W2472016049 hasConcept C192838845 @default.
• W2472016049 hasConcept C20418707 @default.
• W2472016049 hasConcept C2777576037 @default.
• W2472016049 hasConcept C2779222958 @default.
• W2472016049 hasConcept C2779429346 @default.
• W2472016049 hasConcept C29452124 @default.
• W2472016049 hasConcept C30481170 @default.
• W2472016049 hasConcept C47432576 @default.
• W2472016049 hasConcept C55493867 @default.
• W2472016049 hasConcept C70547292 @default.
• W2472016049 hasConcept C85813293 @default.
• W2472016049 hasConcept C86803240 @default.
• W2472016049 hasConcept C93304396 @default.
• W2472016049 hasConcept C95444343 @default.
• W2472016049 hasConceptScore W2472016049C104317684 @default.
• W2472016049 hasConceptScore W2472016049C12554922 @default.
• W2472016049 hasConceptScore W2472016049C1491633281 @default.
• W2472016049 hasConceptScore W2472016049C192838845 @default.
• W2472016049 hasConceptScore W2472016049C20418707 @default.
• W2472016049 hasConceptScore W2472016049C2777576037 @default.
• W2472016049 hasConceptScore W2472016049C2779222958 @default.
• W2472016049 hasConceptScore W2472016049C2779429346 @default.
• W2472016049 hasConceptScore W2472016049C29452124 @default.
• W2472016049 hasConceptScore W2472016049C30481170 @default.
• W2472016049 hasConceptScore W2472016049C47432576 @default.
• W2472016049 hasConceptScore W2472016049C55493867 @default.
• W2472016049 hasConceptScore W2472016049C70547292 @default.
• W2472016049 hasConceptScore W2472016049C85813293 @default.
• W2472016049 hasConceptScore W2472016049C86803240 @default.
• W2472016049 hasConceptScore W2472016049C93304396 @default.
• W2472016049 hasConceptScore W2472016049C95444343 @default.
• W2472016049 hasIssue "3" @default.
• W2472016049 hasLocation W24720160491 @default.
• W2472016049 hasLocation W24720160492 @default.
• W2472016049 hasLocation W24720160493 @default.
• W2472016049 hasLocation W24720160494 @default.
• W2472016049 hasLocation W24720160495 @default.
• W2472016049 hasLocation W24720160496 @default.
• W2472016049 hasOpenAccess W2472016049 @default.
• W2472016049 hasPrimaryLocation W24720160491 @default.
• W2472016049 hasRelatedWork W1943242990 @default.
• W2472016049 hasRelatedWork W2000164138 @default.
• W2472016049 hasRelatedWork W2092654582 @default.
• W2472016049 hasRelatedWork W2125538185 @default.
• W2472016049 hasRelatedWork W2127578593 @default.
• W2472016049 hasRelatedWork W2136961873 @default.
• W2472016049 hasRelatedWork W2226319973 @default.
• W2472016049 hasRelatedWork W2472016049 @default.

• next