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- W2472162980 abstract "Background: Limited data exist on long-term safety and effectiveness of drug-eluting stents (DESs) in true chronic total coronary occlusion (CTO) settings. We evaluated 5-year clinical outcomes of patients with CTO treated successfully with DES vs bare-metal stent (BMS). Methods: We compared the 5-year clinical outcomes of 156 patients treated with DES implantation with outcomes of a historical cohort of 159 patients treated with BMS. Primary end point was freedom from major adverse cardiac events (MACEs; defined as death, myocardial infarction [MI], and target lesion revascularization [TLR]); secondary end points were freedom from target vessel failure (TVF; combination of target vessel revascularization, MI, and cardiac death) and TLR at 5 years. Results: After 5 years, the DES group had significantly superior eventfree survival from MACE (84% vs 69%; log rank P < 0.001), TVF (71% vs 84%; P ¼ 0.002), and TLR (77% vs 92%; P ¼ 0.0001), compared with the BMS group. The Cox proportional hazards model identified BMS vs DES (adjusted hazard ratio [HR] ¼ 3.37; 95% confidence interval [CI], 1.85-6.17; P ¼ 0.001), final minimal lumen diameter (HR, 0.27; 95% CI, 0.14-0.52; P ¼ 0.0001), and stent length (HR, 1.01; 95% CI, 1.00-1.03; P ¼ 0.03) as independent predictors of MACE at RESUME" @default.
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- W2472162980 date "2013-01-01" @default.
- W2472162980 modified "2023-09-27" @default.
- W2472162980 title "Clinical Research Five-Year Outcomes in Patients With Chronic Total Coronary Occlusion Treated With Drug-Eluting vs Bare-Metal Stents: A Case-Control Study" @default.
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