Matches in SemOpenAlex for { <https://semopenalex.org/work/W2472279802> ?p ?o ?g. }
Showing items 1 to 78 of
78
with 100 items per page.
- W2472279802 endingPage "762" @default.
- W2472279802 startingPage "757" @default.
- W2472279802 abstract "Eight triazolopyrimidine sulfonanilides were tested for metabolic stability in a number of crop and weed species. These data, along with in vitro determinations of activity (I 50 ) against acetolactate synthase, successfully described the in vivo activity of these compounds in a two-parameter model. Whole plant activity increased with increasing compound stability and decreasing I 50 (r 2 =.78, N = 36). The difficulty in obtaining metabolic stability data during a structure optimization program prompted a study with substituent parameters in models of in vivo activity. Models describing whole plant activity in jimsonweed were developed using a series of 5-methyl triazolopyrimidine sulfonanilides that differed only in ortho and meta substituents on the aniline ring. The I 50 term and clogP were most important to jimsonweed activity. Hence, in vitro activity (I 50 ) may be a useful component of whole plant structure activity models to aid in identification of barriers to in vivo performance." @default.
- W2472279802 created "2016-07-22" @default.
- W2472279802 creator A5012024559 @default.
- W2472279802 creator A5033334274 @default.
- W2472279802 creator A5036444415 @default.
- W2472279802 creator A5049112901 @default.
- W2472279802 creator A5056773258 @default.
- W2472279802 date "1996-09-01" @default.
- W2472279802 modified "2023-09-26" @default.
- W2472279802 title "Translation of<i>In Vitro</i>Activity to<i>In Vivo</i>Activity: Lessons from the Triazolopyrimidine Sulfonanilides" @default.
- W2472279802 cites W1581959325 @default.
- W2472279802 cites W1996010393 @default.
- W2472279802 cites W2002365910 @default.
- W2472279802 cites W2006062679 @default.
- W2472279802 cites W2013376623 @default.
- W2472279802 cites W2022409221 @default.
- W2472279802 cites W2068936909 @default.
- W2472279802 cites W2081816171 @default.
- W2472279802 cites W347826878 @default.
- W2472279802 cites W4240735936 @default.
- W2472279802 doi "https://doi.org/10.1017/s0043174500094649" @default.
- W2472279802 hasPublicationYear "1996" @default.
- W2472279802 type Work @default.
- W2472279802 sameAs 2472279802 @default.
- W2472279802 citedByCount "2" @default.
- W2472279802 crossrefType "journal-article" @default.
- W2472279802 hasAuthorship W2472279802A5012024559 @default.
- W2472279802 hasAuthorship W2472279802A5033334274 @default.
- W2472279802 hasAuthorship W2472279802A5036444415 @default.
- W2472279802 hasAuthorship W2472279802A5049112901 @default.
- W2472279802 hasAuthorship W2472279802A5056773258 @default.
- W2472279802 hasConcept C150903083 @default.
- W2472279802 hasConcept C181199279 @default.
- W2472279802 hasConcept C185592680 @default.
- W2472279802 hasConcept C198684833 @default.
- W2472279802 hasConcept C202751555 @default.
- W2472279802 hasConcept C207001950 @default.
- W2472279802 hasConcept C2778689049 @default.
- W2472279802 hasConcept C2780785311 @default.
- W2472279802 hasConcept C28212737 @default.
- W2472279802 hasConcept C2991874392 @default.
- W2472279802 hasConcept C55493867 @default.
- W2472279802 hasConcept C71240020 @default.
- W2472279802 hasConcept C86803240 @default.
- W2472279802 hasConceptScore W2472279802C150903083 @default.
- W2472279802 hasConceptScore W2472279802C181199279 @default.
- W2472279802 hasConceptScore W2472279802C185592680 @default.
- W2472279802 hasConceptScore W2472279802C198684833 @default.
- W2472279802 hasConceptScore W2472279802C202751555 @default.
- W2472279802 hasConceptScore W2472279802C207001950 @default.
- W2472279802 hasConceptScore W2472279802C2778689049 @default.
- W2472279802 hasConceptScore W2472279802C2780785311 @default.
- W2472279802 hasConceptScore W2472279802C28212737 @default.
- W2472279802 hasConceptScore W2472279802C2991874392 @default.
- W2472279802 hasConceptScore W2472279802C55493867 @default.
- W2472279802 hasConceptScore W2472279802C71240020 @default.
- W2472279802 hasConceptScore W2472279802C86803240 @default.
- W2472279802 hasIssue "3" @default.
- W2472279802 hasLocation W24722798021 @default.
- W2472279802 hasOpenAccess W2472279802 @default.
- W2472279802 hasPrimaryLocation W24722798021 @default.
- W2472279802 hasRelatedWork W130010948 @default.
- W2472279802 hasRelatedWork W1972665833 @default.
- W2472279802 hasRelatedWork W1974254036 @default.
- W2472279802 hasRelatedWork W1976314208 @default.
- W2472279802 hasRelatedWork W1988259208 @default.
- W2472279802 hasRelatedWork W1988346978 @default.
- W2472279802 hasRelatedWork W2010372900 @default.
- W2472279802 hasRelatedWork W2042153386 @default.
- W2472279802 hasRelatedWork W2374599087 @default.
- W2472279802 hasRelatedWork W412475053 @default.
- W2472279802 hasVolume "44" @default.
- W2472279802 isParatext "false" @default.
- W2472279802 isRetracted "false" @default.
- W2472279802 magId "2472279802" @default.
- W2472279802 workType "article" @default.