Matches in SemOpenAlex for { <https://semopenalex.org/work/W2472404767> ?p ?o ?g. }
Showing items 1 to 87 of
87
with 100 items per page.
- W2472404767 endingPage "9" @default.
- W2472404767 startingPage "55" @default.
- W2472404767 abstract "To observe the effect of electroacupuncture (EA) intervention on spleen T-helper 17 (Th 17) and regulatory T (Treg) cell levels in mice with ulcerative colitis (UC), so as to reveal its mechanisms underlying improvement of UC. METHODS Kunming mice were randomized into control, UC model and EA groups, with 8 mice in each group. The UC model was established by giving the mice with 3% Dextran Sulfate Sodium (DSS) for 5 days. EA (15 Hz/25 Hz, 0.1-0.2 mA) was applied at Guanyuan (CV 4) and bilateral Zusanli (ST 36, used alternatively) for 10 min, once a day for 5 days. The animals' disease activity index [DAl, = (body weight index score + stool score + bleeding score)/3; 0-4 points] were calculated. The pathological changes of colon tissues were observed by light microscopy after H. E. stain, and spleen Treg (CD⁴⁺ CD²⁵⁺ Foxp³⁺ Treg) and Th 17 (CD³⁺ CD⁸⁺ IL-17⁺ Th 17) lymphocyte levels were determined by flow cytometry.Compared to the control group, the DAl score and the ratio of Th 17/CD⁸⁺ T cells were significantly increased, while the ratio of Treg/CD⁴⁺ T cells obviously decreased in the model group (P < 0.05). After EA intervention, the increased DAI score and the ratio of Th 17/CD⁸⁺ T cells and the decreased Treg/CD⁴⁺ T cells were reversed (P < 0.05), and the inflammatory cell infiltration degree of the colon tissue was attenuated.EA intervention can improve the, UC rats' symptoms of activity state, bloody or viscidity stool and colonic inflammation, probably by regulating the balance between the spleenic Treg and Th 17 lymphocytes." @default.
- W2472404767 created "2016-07-22" @default.
- W2472404767 creator A5006615211 @default.
- W2472404767 creator A5035661092 @default.
- W2472404767 creator A5035823034 @default.
- W2472404767 creator A5037711810 @default.
- W2472404767 creator A5044741151 @default.
- W2472404767 creator A5071158259 @default.
- W2472404767 creator A5078766659 @default.
- W2472404767 creator A5091353827 @default.
- W2472404767 date "2016-02-01" @default.
- W2472404767 modified "2023-10-12" @default.
- W2472404767 title "[Effect of Electroacupuncture Stimulation of Guanyuan (CV 4) and Zusanli (ST 36) on Spleen Lymphocytes Treg/Th 17 Immune Balance in Ulcerative Colitis Mice]." @default.
- W2472404767 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/27141622" @default.
- W2472404767 hasPublicationYear "2016" @default.
- W2472404767 type Work @default.
- W2472404767 sameAs 2472404767 @default.
- W2472404767 citedByCount "1" @default.
- W2472404767 countsByYear W24724047672023 @default.
- W2472404767 crossrefType "journal-article" @default.
- W2472404767 hasAuthorship W2472404767A5006615211 @default.
- W2472404767 hasAuthorship W2472404767A5035661092 @default.
- W2472404767 hasAuthorship W2472404767A5035823034 @default.
- W2472404767 hasAuthorship W2472404767A5037711810 @default.
- W2472404767 hasAuthorship W2472404767A5044741151 @default.
- W2472404767 hasAuthorship W2472404767A5071158259 @default.
- W2472404767 hasAuthorship W2472404767A5078766659 @default.
- W2472404767 hasAuthorship W2472404767A5091353827 @default.
- W2472404767 hasConcept C126322002 @default.
- W2472404767 hasConcept C134018914 @default.
- W2472404767 hasConcept C142724271 @default.
- W2472404767 hasConcept C203014093 @default.
- W2472404767 hasConcept C204232928 @default.
- W2472404767 hasConcept C204787440 @default.
- W2472404767 hasConcept C24998067 @default.
- W2472404767 hasConcept C2775862500 @default.
- W2472404767 hasConcept C2776202274 @default.
- W2472404767 hasConcept C2776460901 @default.
- W2472404767 hasConcept C2776914184 @default.
- W2472404767 hasConcept C2779134260 @default.
- W2472404767 hasConcept C2779504368 @default.
- W2472404767 hasConcept C2780479503 @default.
- W2472404767 hasConcept C2780931953 @default.
- W2472404767 hasConcept C56837625 @default.
- W2472404767 hasConcept C71924100 @default.
- W2472404767 hasConcept C8891405 @default.
- W2472404767 hasConcept C90924648 @default.
- W2472404767 hasConceptScore W2472404767C126322002 @default.
- W2472404767 hasConceptScore W2472404767C134018914 @default.
- W2472404767 hasConceptScore W2472404767C142724271 @default.
- W2472404767 hasConceptScore W2472404767C203014093 @default.
- W2472404767 hasConceptScore W2472404767C204232928 @default.
- W2472404767 hasConceptScore W2472404767C204787440 @default.
- W2472404767 hasConceptScore W2472404767C24998067 @default.
- W2472404767 hasConceptScore W2472404767C2775862500 @default.
- W2472404767 hasConceptScore W2472404767C2776202274 @default.
- W2472404767 hasConceptScore W2472404767C2776460901 @default.
- W2472404767 hasConceptScore W2472404767C2776914184 @default.
- W2472404767 hasConceptScore W2472404767C2779134260 @default.
- W2472404767 hasConceptScore W2472404767C2779504368 @default.
- W2472404767 hasConceptScore W2472404767C2780479503 @default.
- W2472404767 hasConceptScore W2472404767C2780931953 @default.
- W2472404767 hasConceptScore W2472404767C56837625 @default.
- W2472404767 hasConceptScore W2472404767C71924100 @default.
- W2472404767 hasConceptScore W2472404767C8891405 @default.
- W2472404767 hasConceptScore W2472404767C90924648 @default.
- W2472404767 hasIssue "1" @default.
- W2472404767 hasLocation W24724047671 @default.
- W2472404767 hasOpenAccess W2472404767 @default.
- W2472404767 hasPrimaryLocation W24724047671 @default.
- W2472404767 hasRelatedWork W1984619393 @default.
- W2472404767 hasRelatedWork W1994554879 @default.
- W2472404767 hasRelatedWork W2034768996 @default.
- W2472404767 hasRelatedWork W2060075063 @default.
- W2472404767 hasRelatedWork W2060618991 @default.
- W2472404767 hasRelatedWork W2064416809 @default.
- W2472404767 hasRelatedWork W2163700154 @default.
- W2472404767 hasRelatedWork W2366108000 @default.
- W2472404767 hasRelatedWork W2371187173 @default.
- W2472404767 hasRelatedWork W4200106852 @default.
- W2472404767 hasVolume "41" @default.
- W2472404767 isParatext "false" @default.
- W2472404767 isRetracted "false" @default.
- W2472404767 magId "2472404767" @default.
- W2472404767 workType "article" @default.