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- W2472423061 abstract "The possibility of the evaluation of ischaemia solely by the momentary values of regional cerebral blood flow (rCBF) was investigated. Ischaemic damage was evaluated histopathologi-cally and by observing albumin extravasation. Unilateral carotid clippings were performed for 1 h and the gerbils evaluated with regard to the length of recirculation time. In animals without a recirculation period’, the degree of damage could be explained by the rCBF reduction ratio during clipping. However, in cases with reperfusion periods, 5 animals showed an almost complete disappearance of rCBF during clipping, but albumin extravasation was seen in 1 case only. Thus, the discordance between the rCBF reduction ratio and the abnormal permeability was considerable in reperfused animals. The post-ischaemic rCBF pattern was classified into 3 types, the ‘post-ischaemic hyperperfusion type’, the ‘post-ischaemic hypoperfusion type’ and the ‘post-ischaemic normopeiiusion type’. In the first two types, the albumin extravasation was positive in 10/10 cases, and in the third type, in only 1/20. Therefore, the post-ischaemic rCBF pattern was thought to correlate well with ischaemic damage in the reperfused cases. The rCBF changes momentarily and the pattern analysis of the rCBF, particularly in the post-ischaemic phase, appeared to be important." @default.
- W2472423061 created "2016-07-22" @default.
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- W2472423061 date "1988-12-01" @default.
- W2472423061 modified "2023-10-16" @default.
- W2472423061 title "Regional cerebral blood flow (rCBF) pattern analysis corresponds with albumin extravasation in experimental cerebral ischaemia" @default.
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- W2472423061 doi "https://doi.org/10.1080/01616412.1988.11739846" @default.
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