FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2473376802> ?p ?o ?g. }

• W2473376802 endingPage "1067" @default.
• W2473376802 startingPage "1058" @default.
• W2473376802 abstract "Both the complement system and collectins play important roles in our innate immune system. The collectins, which are characterized by their inclusion of a collagen-like region and a calcium-dependent carbohydrate recognition domain, are pattern recognition molecules and include the well characterized proteins mannan-binding lectin (MBL) and the surfactant proteins SP-A/-D. Collectin liver 1 (CL-L1), collectin kidney 1 (CL-K1) and collectin placenta 1 (CL-P1) are the most recently discovered collectins. Although their function is still under investigation, accumulating information suggests that CL-L1, CL-K1 and CL-P1 play important roles in host defense by recognizing a variety of microorganisms and interacting with effector proteins, including complement components. The recent establishment of the existence of CL-K1 in the circulation in form of heteromeric complexes with CL-L1 (known as CL-LK) and its activation of the lectin pathway via MASPs, drew new attention in the complement biology, which was further strengthened by the observed interactions between CL-P1 and CRP-C1q-factor H or properdin. Deficiency of either CL-K1 or MASP-3 has been demonstrated in 3MC syndrome patients with developmental abnormalities, showing that lectin pathway components, regulation and/or activation are essential during the embryonic development; another feature that they most likely share CL-P1. Herein, we discuss the recent characteristics and roles of the collectins CL-L1, CL-K1 and CL-P1 in the complement system, in innate immunity and their possible association with disease development and pathogenesis." @default.
• W2473376802 created "2016-07-22" @default.
• W2473376802 creator A5009312747 @default.
• W2473376802 creator A5031537863 @default.
• W2473376802 creator A5058824719 @default.
• W2473376802 creator A5074321510 @default.
• W2473376802 date "2016-10-01" @default.
• W2473376802 modified "2023-10-06" @default.
• W2473376802 title "The collectins CL-L1, CL-K1 and CL-P1, and their roles in complement and innate immunity" @default.
• W2473376802 cites W1557343619 @default.
• W2473376802 cites W1575864987 @default.
• W2473376802 cites W1767274962 @default.
• W2473376802 cites W1968057579 @default.
• W2473376802 cites W1968272594 @default.
• W2473376802 cites W1970115530 @default.
• W2473376802 cites W1970365484 @default.
• W2473376802 cites W1982642399 @default.
• W2473376802 cites W1984990327 @default.
• W2473376802 cites W1987515900 @default.
• W2473376802 cites W1992180550 @default.
• W2473376802 cites W1995611890 @default.
• W2473376802 cites W1997121975 @default.
• W2473376802 cites W2024180890 @default.
• W2473376802 cites W2025153892 @default.
• W2473376802 cites W2030385147 @default.
• W2473376802 cites W2030545744 @default.
• W2473376802 cites W2040087478 @default.
• W2473376802 cites W2043296206 @default.
• W2473376802 cites W2044250870 @default.
• W2473376802 cites W2054292263 @default.
• W2473376802 cites W2055570398 @default.
• W2473376802 cites W2061921891 @default.
• W2473376802 cites W2064648040 @default.
• W2473376802 cites W2068795221 @default.
• W2473376802 cites W2070608700 @default.
• W2473376802 cites W2071292091 @default.
• W2473376802 cites W2076081730 @default.
• W2473376802 cites W2076865759 @default.
• W2473376802 cites W2077407314 @default.
• W2473376802 cites W2078281513 @default.
• W2473376802 cites W2090890529 @default.
• W2473376802 cites W2101393471 @default.
• W2473376802 cites W2103860066 @default.
• W2473376802 cites W2114727194 @default.
• W2473376802 cites W2130420735 @default.
• W2473376802 cites W2136220283 @default.
• W2473376802 cites W2136347383 @default.
• W2473376802 cites W2140520351 @default.
• W2473376802 cites W2143507280 @default.
• W2473376802 cites W2149039469 @default.
• W2473376802 cites W2162915566 @default.
• W2473376802 cites W2274667968 @default.
• W2473376802 cites W2291348653 @default.
• W2473376802 cites W2317184793 @default.
• W2473376802 cites W2340799290 @default.
• W2473376802 cites W2417768820 @default.
• W2473376802 cites W332217229 @default.
• W2473376802 cites W426573286 @default.
• W2473376802 doi "https://doi.org/10.1016/j.imbio.2016.05.012" @default.
• W2473376802 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/27377710" @default.
• W2473376802 hasPublicationYear "2016" @default.
• W2473376802 type Work @default.
• W2473376802 sameAs 2473376802 @default.
• W2473376802 citedByCount "62" @default.
• W2473376802 countsByYear W24733768022016 @default.
• W2473376802 countsByYear W24733768022017 @default.
• W2473376802 countsByYear W24733768022018 @default.
• W2473376802 countsByYear W24733768022019 @default.
• W2473376802 countsByYear W24733768022020 @default.
• W2473376802 countsByYear W24733768022021 @default.
• W2473376802 countsByYear W24733768022022 @default.
• W2473376802 countsByYear W24733768022023 @default.
• W2473376802 crossrefType "journal-article" @default.
• W2473376802 hasAuthorship W2473376802A5009312747 @default.
• W2473376802 hasAuthorship W2473376802A5031537863 @default.
• W2473376802 hasAuthorship W2473376802A5058824719 @default.
• W2473376802 hasAuthorship W2473376802A5074321510 @default.
• W2473376802 hasBestOaLocation W24733768022 @default.
• W2473376802 hasConcept C111684460 @default.
• W2473376802 hasConcept C133493029 @default.
• W2473376802 hasConcept C136449434 @default.
• W2473376802 hasConcept C171279029 @default.
• W2473376802 hasConcept C189446657 @default.
• W2473376802 hasConcept C193419808 @default.
• W2473376802 hasConcept C203014093 @default.
• W2473376802 hasConcept C203880312 @default.
• W2473376802 hasConcept C2780758401 @default.
• W2473376802 hasConcept C7407320 @default.
• W2473376802 hasConcept C86803240 @default.
• W2473376802 hasConcept C8891405 @default.
• W2473376802 hasConcept C95444343 @default.
• W2473376802 hasConceptScore W2473376802C111684460 @default.
• W2473376802 hasConceptScore W2473376802C133493029 @default.
• W2473376802 hasConceptScore W2473376802C136449434 @default.
• W2473376802 hasConceptScore W2473376802C171279029 @default.
• W2473376802 hasConceptScore W2473376802C189446657 @default.
• W2473376802 hasConceptScore W2473376802C193419808 @default.
• W2473376802 hasConceptScore W2473376802C203014093 @default.

• next