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• W2473453403 endingPage "e0157821" @default.
• W2473453403 startingPage "e0157821" @default.
• W2473453403 abstract "Cephalopods provide an unprecedented opportunity for comparative studies of the developmental genetics of organ systems that are convergent with analogous vertebrate structures. The Sox-family of transcription factors is an important class of DNA-binding proteins that are known to be involved in many aspects of differentiation, but have been largely unstudied in lophotrochozoan systems. Using a degenerate primer strategy we have isolated coding sequence for three members of the Sox family of transcription factors from a cephalopod mollusk, the European cuttlefish Sepia officinalis: Sof-SoxE, Sof-SoxB1, and Sof-SoxB2. Analyses of their expression patterns during organogenesis reveals distinct spatial and temporal expression domains. Sof-SoxB1 shows early ectodermal expression throughout the developing epithelium, which is gradually restricted to presumptive sensory epithelia. Expression within the nervous system appears by mid-embryogenesis. Sof-SoxB2 expression is similar to Sof-SoxB1 within the developing epithelia in early embryogenesis, however appears in largely non-overlapping expression domains within the central nervous system and is not expressed in the maturing sensory epithelium. In contrast, Sof-SoxE is expressed throughout the presumptive mesodermal territories at the onset of organogenesis. As development proceeds, Sof-SoxE expression is elevated throughout the developing peripheral circulatory system. This expression disappears as the circulatory system matures, but expression is maintained within undifferentiated connective tissues throughout the animal, and appears within the nervous system near the end of embryogenesis. SoxB proteins are widely known for their role in neural specification in numerous phylogenetic lineages. Our data suggests that Sof-SoxB genes play similar roles in cephalopods. In contrast, Sof-SoxE appears to be involved in the early stages of vasculogenesis of the cephalopod closed circulatory system, a novel role for a member of this gene family." @default.
• W2473453403 created "2016-07-22" @default.
• W2473453403 creator A5041132810 @default.
• W2473453403 creator A5069723166 @default.
• W2473453403 date "2016-06-22" @default.
• W2473453403 modified "2023-10-16" @default.
• W2473453403 title "Analyses of Sox-B and Sox-E Family Genes in the Cephalopod Sepia officinalis: Revealing the Conserved and the Unusual" @default.
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• W2473453403 cites W1976554440 @default.
• W2473453403 cites W1979112791 @default.
• W2473453403 cites W1979599046 @default.
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• W2473453403 doi "https://doi.org/10.1371/journal.pone.0157821" @default.
• W2473453403 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4917168" @default.
• W2473453403 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/27331398" @default.
• W2473453403 hasPublicationYear "2016" @default.
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