Matches in SemOpenAlex for { <https://semopenalex.org/work/W2473605897> ?p ?o ?g. }
Showing items 1 to 76 of
76
with 100 items per page.
- W2473605897 abstract "Purpose:Scatter contamination is detrimental to image quality in dedicated cone-beam breast CT (CBBCT), resulting in cupping artifacts and loss of contrast in reconstructed images. Such effects impede visualization of breast lesions and the quantitative accuracy. Previously, we proposed a library-based software approach to suppress scatter on CBBCT images. In this work, we quantify the efficacy and stability of this approach using datasets from 15 human subjects.Methods:A pre-computed scatter library is generated using Monte Carlo simulations for semi-ellipsoid breast models and homogeneous fibroglandular/adipose tissue mixture encompassing the range reported in literature. Projection datasets from 15 human subjects that cover 95 percentile of breast dimensions and fibroglandular volume fraction were included in the analysis. Our investigations indicate that it is sufficient to consider the breast dimensions alone and variation in fibroglandular fraction does not significantly affect the scatter-to-primary ratio. The breast diameter is measured from a first-pass reconstruction; the appropriate scatter distribution is selected from the library; and, deformed by considering the discrepancy in total projection intensity between the clinical dataset and the simulated semi-ellipsoidal breast. The deformed scatter-distribution is subtracted from the measured projections for scatter correction. Spatial non-uniformity (SNU) and contrast-to-noise ratio (CNR) were used as quantitative metrics to evaluate the results.Results:On the 15 patient cases, our method reduced the overall image spatial non-uniformity (SNU) from 7.14%±2.94% (mean ± standard deviation) to 2.47%±0.68% in coronal view and from 10.14%±4.1% to 3.02% ±1.26% in sagittal view. The average contrast to noise ratio (CNR) improved by a factor of 1.49±0.40 in coronal view and by 2.12±1.54 in sagittal view.Conclusion:We demonstrate the robustness and effectiveness of a library-based scatter correction method using patient datasets with large variability in breast dimensions and composition. The high computational efficiency and simplicity in implementation make this attractive for clinical implementation.Supported partly by NIH R21EB019597, R21CA134128 and R01CA195512.The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health." @default.
- W2473605897 created "2016-07-22" @default.
- W2473605897 creator A5015178970 @default.
- W2473605897 creator A5035554383 @default.
- W2473605897 creator A5058544467 @default.
- W2473605897 creator A5064419586 @default.
- W2473605897 date "2016-06-01" @default.
- W2473605897 modified "2023-10-02" @default.
- W2473605897 title "WE-DE-207B-10: Library-Based X-Ray Scatter Correction for Dedicated Cone-Beam Breast CT: Clinical Validation" @default.
- W2473605897 doi "https://doi.org/10.1118/1.4957870" @default.
- W2473605897 hasPublicationYear "2016" @default.
- W2473605897 type Work @default.
- W2473605897 sameAs 2473605897 @default.
- W2473605897 citedByCount "0" @default.
- W2473605897 crossrefType "journal-article" @default.
- W2473605897 hasAuthorship W2473605897A5015178970 @default.
- W2473605897 hasAuthorship W2473605897A5035554383 @default.
- W2473605897 hasAuthorship W2473605897A5058544467 @default.
- W2473605897 hasAuthorship W2473605897A5064419586 @default.
- W2473605897 hasConcept C104293457 @default.
- W2473605897 hasConcept C105795698 @default.
- W2473605897 hasConcept C11413529 @default.
- W2473605897 hasConcept C120665830 @default.
- W2473605897 hasConcept C121332964 @default.
- W2473605897 hasConcept C122048520 @default.
- W2473605897 hasConcept C126838900 @default.
- W2473605897 hasConcept C19499675 @default.
- W2473605897 hasConcept C22679943 @default.
- W2473605897 hasConcept C2779813781 @default.
- W2473605897 hasConcept C2989005 @default.
- W2473605897 hasConcept C33923547 @default.
- W2473605897 hasConcept C544519230 @default.
- W2473605897 hasConcept C57493831 @default.
- W2473605897 hasConcept C71924100 @default.
- W2473605897 hasConceptScore W2473605897C104293457 @default.
- W2473605897 hasConceptScore W2473605897C105795698 @default.
- W2473605897 hasConceptScore W2473605897C11413529 @default.
- W2473605897 hasConceptScore W2473605897C120665830 @default.
- W2473605897 hasConceptScore W2473605897C121332964 @default.
- W2473605897 hasConceptScore W2473605897C122048520 @default.
- W2473605897 hasConceptScore W2473605897C126838900 @default.
- W2473605897 hasConceptScore W2473605897C19499675 @default.
- W2473605897 hasConceptScore W2473605897C22679943 @default.
- W2473605897 hasConceptScore W2473605897C2779813781 @default.
- W2473605897 hasConceptScore W2473605897C2989005 @default.
- W2473605897 hasConceptScore W2473605897C33923547 @default.
- W2473605897 hasConceptScore W2473605897C544519230 @default.
- W2473605897 hasConceptScore W2473605897C57493831 @default.
- W2473605897 hasConceptScore W2473605897C71924100 @default.
- W2473605897 hasLocation W24736058971 @default.
- W2473605897 hasOpenAccess W2473605897 @default.
- W2473605897 hasPrimaryLocation W24736058971 @default.
- W2473605897 hasRelatedWork W1963561736 @default.
- W2473605897 hasRelatedWork W1994375338 @default.
- W2473605897 hasRelatedWork W2001374473 @default.
- W2473605897 hasRelatedWork W2008671668 @default.
- W2473605897 hasRelatedWork W2023187868 @default.
- W2473605897 hasRelatedWork W2029613468 @default.
- W2473605897 hasRelatedWork W2033082699 @default.
- W2473605897 hasRelatedWork W2047058304 @default.
- W2473605897 hasRelatedWork W2068433686 @default.
- W2473605897 hasRelatedWork W2118583314 @default.
- W2473605897 hasRelatedWork W2140098770 @default.
- W2473605897 hasRelatedWork W2152392784 @default.
- W2473605897 hasRelatedWork W2295937319 @default.
- W2473605897 hasRelatedWork W2469478704 @default.
- W2473605897 hasRelatedWork W2793682772 @default.
- W2473605897 hasRelatedWork W2889260661 @default.
- W2473605897 hasRelatedWork W3015463110 @default.
- W2473605897 hasRelatedWork W3019667561 @default.
- W2473605897 hasRelatedWork W3129550636 @default.
- W2473605897 hasRelatedWork W798128625 @default.
- W2473605897 isParatext "false" @default.
- W2473605897 isRetracted "false" @default.
- W2473605897 magId "2473605897" @default.
- W2473605897 workType "article" @default.