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• W2473645707 abstract "No AccessJournal of Urology1 Jul 1983Hematoporphyrin Derivative and Laser Photoradiation in the Diagnosis and Treatment of Bladder Cancer Akira Tsuchiya, Nobuo Obara, Makoto Miwa, Tetsutaro Ohi, Harubumi Kato, and Yoshihiro Hayata Akira TsuchiyaAkira Tsuchiya More articles by this author , Nobuo ObaraNobuo Obara More articles by this author , Makoto MiwaMakoto Miwa More articles by this author , Tetsutaro OhiTetsutaro Ohi More articles by this author , Harubumi KatoHarubumi Kato More articles by this author , and Yoshihiro HayataYoshihiro Hayata More articles by this author View All Author Informationhttps://doi.org/10.1016/S0022-5347(17)50965-9AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Diagnosis and treatment of 8 patients with malignant bladder tumors were performed with intravenous administration of hematoporphyrin derivative, followed by krypton-ion laser violet light photo radiation and argon-dye laser red light photo radiation therapy. Fluorescence permitting localization and evaluation of the lesion was recognized in all 8 patients. Photo radiation with red argon-dye laser light obtained complete remission in 6 patients, with follow up from 6 to 18 months. To our knowledge this is the first report describing total regression of bladder tumors obtained byphotoradiation. Swelling and edema were noted within 20 minutes after argon-dye laser photo radiation therapy of bladder tumors. Necrosis and partial covering of the tumor by a whitish necrotic mass were noted after 3 days. The whitish mass covered the entire tumor at 7 to 14 days. Gradual exfoliation of the mass was followed by disappearance of the tumor and regeneration of normal mucosa at 9 to 10 weeks. © 1983 by The American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetailsCited byAnidjar M, Cussenot O, Blais J, Bourdon O, Avrillier S, Ettori D, Villette J, Fiet J, Teillac P and Le Duc A (2018) Argon Laser Induced Autofluorescence May Distinguish Between Normal and Tumor Human Urothelial Cells: A Microspectrofluorimetric StudyJournal of Urology, VOL. 155, NO. 5, (1771-1774), Online publication date: 1-May-1996.Chang S, MacRobert A and Bown S (2018) Photodynamic Therapy on Rat Urinary Bladder with Intravesical Instillation of 5-Aminolevulinic Acid: Light Diffusion and Histological ChangesJournal of Urology, VOL. 155, NO. 5, (1749-1753), Online publication date: 1-May-1996.Marynissen J, Jansen H and Star W (2018) Treatment System for Whole Bladder Wall Photodynamic Therapy with in Vivo Monitoring and Control of Light Dose Rate and DoseJournal of Urology, VOL. 142, NO. 5, (1351-1355), Online publication date: 1-Nov-1989.Harty J, Amin M, Wieman T, Tseng M, Ackerman D and Broghamer W (2018) Complications of Whole Bladder Dihematoporphyrin Ether Photodynamic TherapyJournal of Urology, VOL. 141, NO. 6, (1341-1346), Online publication date: 1-Jun-1989.Manyak M, Matthews D, Smith P, Nochomovitz L, Glatstein E and Russo A (2018) Response of Normal Canine Ureter to Photodynamic Therapy Using a Cylindrical FiberJournal of Urology, VOL. 139, NO. 1, (199-203), Online publication date: 1-Jan-1988.Benson R (2018) Treatment of Diffuse Transitional Cell Carcinoma in Situ by Whole Bladder Hematoporphyrin Derivative Photodynamic TherapyJournal of Urology, VOL. 134, NO. 4, (675-678), Online publication date: 1-Oct-1985.Williams R (2018) Editorial CommentJournal of Urology, VOL. 134, NO. 4, (678-678), Online publication date: 1-Oct-1985.Selman S, Milligan A, Kreimer-Birnbaum M, Keck R, Goldblatt P and Britton S (2018) Hematoporphyrin Derivative Photochemotherapy of Experimental Bladder TumorsJournal of Urology, VOL. 133, NO. 2, (330-333), Online publication date: 1-Feb-1985. Volume 130Issue 1July 1983Page: 79-82 Advertisement Copyright & Permissions© 1983 by The American Urological Association Education and Research, Inc.MetricsAuthor Information Akira Tsuchiya More articles by this author Nobuo Obara More articles by this author Makoto Miwa More articles by this author Tetsutaro Ohi More articles by this author Harubumi Kato More articles by this author Yoshihiro Hayata More articles by this author Expand All Advertisement PDF downloadLoading ..." @default.
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