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• W2473661358 abstract "We herein report the case of an 80-year-old man with malignant lymphoma who became persistently infected with influenza A virus. Although he was repeatedly treated with NA inhibitors, such as oseltamivir or peramivir, nasal cavity swab tests for influenza A antigen continued to be positive for more than 2 months. Virological analyses revealed that he was infected with the NA inhibitor-resistant A (H3N2) virus possessing an R292K substitution in the NA protein. These findings suggest that a drug-resistant influenza virus strain might selectively survive antiviral therapy in elderly patients with refractory malignant lymphoma undergoing multiple chemotherapies." @default.
• W2473661358 created "2016-07-22" @default.
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• W2473661358 date "2016-01-01" @default.
• W2473661358 modified "2023-10-08" @default.
• W2473661358 title "Persistent Infection of Drug-resistant Influenza A Virus during Chemotherapy for Malignant Lymphoma" @default.
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• W2473661358 doi "https://doi.org/10.2169/internalmedicine.55.6327" @default.
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