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- W2473770518 abstract "No therapeutic effectiveness without unwanted side-effects. This well-known problem persists in spite of modern methods for development of new drugs. Therefore no drug-therapy should be initiated without exact risk-benefit-analysis. Especially for drugs introduced recently, effectiveness is better defined than tolerance. In the USA annual costs of 3 million $ due to drug-side-effects have been estimated, indicating an immense socio-economic relevance next to medical or personal aspects. Therefore effective means and strategies should be accepted and used: General reduction of drug consumption, avoidance of polytherapy with respect to known and unknown interaction of side-effects, strict observation of proper indications, amelioration of surveillance for recently introduced drugs and better consideration of special populations at risk." @default.
- W2473770518 created "2016-07-22" @default.
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- W2473770518 date "1989-03-21" @default.
- W2473770518 modified "2023-10-18" @default.
- W2473770518 title "[Developments in drugs and populations at risk]." @default.
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- W2473770518 hasPublicationYear "1989" @default.
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